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ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.
Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. Sullivan KD, et al. Among authors: porter cc. Nat Chem Biol. 2012 Jul;8(7):646-54. doi: 10.1038/nchembio.965. Epub 2012 Jun 3. Nat Chem Biol. 2012. PMID: 22660439 Free PMC article.
Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.
Casás-Selves M, Kim J, Zhang Z, Helfrich BA, Gao D, Porter CC, Scarborough HA, Bunn PA Jr, Chan DC, Tan AC, DeGregori J. Casás-Selves M, et al. Among authors: porter cc. Cancer Res. 2012 Aug 15;72(16):4154-64. doi: 10.1158/0008-5472.CAN-11-2848. Epub 2012 Jun 27. Cancer Res. 2012. PMID: 22738915 Free PMC article.
138 results