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Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.
Cancer Res. 2010 Apr 1;70(7):2840-51. doi: 10.1158/0008-5472.CAN-09-3155. Epub 2010 Mar 23.
Cancer Res. 2010.
PMID: 20332234
Free PMC article.
Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers.
Stratford AL, Reipas K, Hu K, Fotovati A, Brough R, Frankum J, Takhar M, Watson P, Ashworth A, Lord CJ, Lasham A, Print CG, Dunn SE.
Stratford AL, et al.
Stem Cells. 2012 Jul;30(7):1338-48. doi: 10.1002/stem.1128.
Stem Cells. 2012.
PMID: 22674792
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Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells.
Davies AH, Reipas K, Hu K, Berns R, Firmino N, Stratford AL, Dunn SE.
Davies AH, et al.
Oncotarget. 2015 Aug 21;6(24):20570-7. doi: 10.18632/oncotarget.4135.
Oncotarget. 2015.
PMID: 26011941
Free PMC article.
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YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.
Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE.
Davies AH, et al. Among authors: reipas km.
Stem Cells. 2014 Jun;32(6):1437-50. doi: 10.1002/stem.1707.
Stem Cells. 2014.
PMID: 24648416
Free PMC article.
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Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.
Stratford AL, Reipas K, Maxwell C, Dunn SE.
Stratford AL, et al.
Expert Rev Mol Med. 2010 Jul 26;12:e22. doi: 10.1017/S1462399410001535.
Expert Rev Mol Med. 2010.
PMID: 20653987
Review.
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Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).
Reipas KM, Law JH, Couto N, Islam S, Li Y, Li H, Cherkasov A, Jung K, Cheema AS, Jones SJ, Hassell JA, Dunn SE.
Reipas KM, et al.
Oncotarget. 2013 Feb;4(2):329-45. doi: 10.18632/oncotarget.834.
Oncotarget. 2013.
PMID: 23593654
Free PMC article.
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Examining the Characteristics of Patients With Non-Malignant Lung Disease at the Time of Referral to An Inter-Professional Supportive Care Clinic.
Reipas KM, Grossman DL, Lock K, Caraiscos VB.
Reipas KM, et al.
Am J Hosp Palliat Care. 2021 Nov;38(11):1329-1335. doi: 10.1177/10499091211005698. Epub 2021 Apr 7.
Am J Hosp Palliat Care. 2021.
PMID: 33823617
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