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Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes.
Aoki H, Ke L, Poppe SM, Poel TJ, Weaver EA, Gadwood RC, Thomas RC, Shinabarger DL, Ganoza MC. Aoki H, et al. Antimicrob Agents Chemother. 2002 Apr;46(4):1080-5. doi: 10.1128/AAC.46.4.1080-1085.2002. Antimicrob Agents Chemother. 2002. PMID: 11897593 Free PMC article.
U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication.
Dueweke TJ, Poppe SM, Romero DL, Swaney SM, So AG, Downey KM, Althaus IW, Reusser F, Busso M, Resnick L, et al. Dueweke TJ, et al. Among authors: poppe sm. Antimicrob Agents Chemother. 1993 May;37(5):1127-31. doi: 10.1128/AAC.37.5.1127. Antimicrob Agents Chemother. 1993. PMID: 7685995 Free PMC article.
(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes.
Olmsted RA, Slade DE, Kopta LA, Poppe SM, Poel TJ, Newport SW, Rank KB, Biles C, Morge RA, Dueweke TJ, Yagi Y, Romero DL, Thomas RC, Sharma SK, Tarpley WG. Olmsted RA, et al. Among authors: poppe sm. J Virol. 1996 Jun;70(6):3698-705. doi: 10.1128/JVI.70.6.3698-3705.1996. J Virol. 1996. PMID: 8648704 Free PMC article.
(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.
Wishka DG, Graber DR, Kopta LA, Olmsted RA, Friis JM, Hosley JD, Adams WJ, Seest EP, Castle TM, Dolak LA, Keiser BJ, Yagi Y, Jeganathan A, Schlachter ST, Murphy MJ, Cleek GJ, Nugent RA, Poppe SM, Swaney SM, Han F, Watt W, White WL, Poel TJ, Thomas RC, Morris J, et al. Wishka DG, et al. Among authors: poppe sm. J Med Chem. 1998 Apr 23;41(9):1357-60. doi: 10.1021/jm9801049. J Med Chem. 1998. PMID: 9554867 No abstract available.
136 results