Porubsky PR - Search Results

1

Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode.

Porubsky PR, Battaile KP, Scott EE. Porubsky PR, et al. J Biol Chem. 2010 Jul 16;285(29):22282-90. doi: 10.1074/jbc.M110.109017. Epub 2010 May 12. J Biol Chem. 2010. PMID: 20463018 Free PMC article.

2

Structure of the human lung cytochrome P450 2A13.

Smith BD, Sanders JL, Porubsky PR, Lushington GH, Stout CD, Scott EE. Smith BD, et al. Among authors: porubsky pr. J Biol Chem. 2007 Jun 8;282(23):17306-13. doi: 10.1074/jbc.M702361200. Epub 2007 Apr 11. J Biol Chem. 2007. PMID: 17428784 Free article.

3

Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.

Porubsky PR, Meneely KM, Scott EE. Porubsky PR, et al. J Biol Chem. 2008 Nov 28;283(48):33698-707. doi: 10.1074/jbc.M805999200. Epub 2008 Sep 24. J Biol Chem. 2008. PMID: 18818195 Free PMC article.

4

Structures of human steroidogenic cytochrome P450 17A1 with substrates.

Petrunak EM, DeVore NM, Porubsky PR, Scott EE. Petrunak EM, et al. Among authors: porubsky pr. J Biol Chem. 2014 Nov 21;289(47):32952-64. doi: 10.1074/jbc.M114.610998. Epub 2014 Oct 9. J Biol Chem. 2014. PMID: 25301938 Free PMC article.

5

p-dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/vis-MS/MS identification of indoles.

Porubsky PR, Scott EE, Williams TD. Porubsky PR, et al. Arch Biochem Biophys. 2008 Jul 1;475(1):14-7. doi: 10.1016/j.abb.2008.03.035. Epub 2008 Apr 7. Arch Biochem Biophys. 2008. PMID: 18423367 Free PMC article.

6

Exploring chemical diversity via a modular reaction pairing strategy.

Loh JK, Yoon SY, Samarakoon TB, Rolfe A, Porubsky P, Neuenswander B, Lushington GH, Hanson PR. Loh JK, et al. Among authors: porubsky p. Beilstein J Org Chem. 2012;8:1293-302. doi: 10.3762/bjoc.8.147. Epub 2012 Aug 15. Beilstein J Org Chem. 2012. PMID: 23019462 Free PMC article.

7

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.

Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Lopez Quezada L, Somersan S, Warrier T, Little D, Pingle M, Zhang D, Ballinger E, Zimmerman M, Dartois V, Hanson P, Mitscher LA, Porubsky P, Rogers S, Schoenen FJ, Nathan C, Aubé J. Gold B, et al. J Med Chem. 2016 Jul 14;59(13):6027-44. doi: 10.1021/acs.jmedchem.5b01833. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27144688 Free PMC article.

8

Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

Zang Q, Javed S, Porubsky P, Ullah F, Neuenswander B, Lushington GH, Basha FZ, Organ MG, Hanson PR. Zang Q, et al. Among authors: porubsky p. ACS Comb Sci. 2012 Mar 12;14(3):211-7. doi: 10.1021/co200181x. Epub 2012 Feb 6. ACS Comb Sci. 2012. PMID: 22311745 Free PMC article.

9

Triazole-containing isothiazolidine 1,1-dioxide library synthesis: one-pot, multi-component protocols for small molecular probe discovery.

Rolfe A, Painter TO, Asad N, Hur MY, Jeon KO, Brzozowski M, Klimberg SV, Porubsky P, Neuenswander B, Lushington GH, Santini C, Hanson PR. Rolfe A, et al. Among authors: porubsky p. ACS Comb Sci. 2011 Sep 12;13(5):511-7. doi: 10.1021/co200093c. Epub 2011 Aug 25. ACS Comb Sci. 2011. PMID: 21866904 Free PMC article.

10

Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.

Faisal S, Ullah F, Maity PK, Rolfe A, Samarakoon TB, Porubsky P, Neuenswander B, Lushington GH, Basha FZ, Organ MG, Hanson PR. Faisal S, et al. Among authors: porubsky p. ACS Comb Sci. 2012 Apr 9;14(4):268-72. doi: 10.1021/co2001839. Epub 2012 Mar 5. ACS Comb Sci. 2012. PMID: 22384820 Free PMC article.

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