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Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones.
Peukert S, Sun Y, Zhang R, Hurley B, Sabio M, Shen X, Gray C, Dzink-Fox J, Tao J, Cebula R, Wattanasin S. Peukert S, et al. Among authors: tao j. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1840-4. doi: 10.1016/j.bmcl.2008.02.009. Epub 2008 Feb 10. Bioorg Med Chem Lett. 2008. PMID: 18295483
Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
Richie DL, Thompson KV, Studer C, Prindle VC, Aust T, Riedl R, Estoppey D, Tao J, Sexton JA, Zabawa T, Drumm J, Cotesta S, Eichenberger J, Schuierer S, Hartmann N, Movva NR, Tallarico JA, Ryder NS, Hoepfner D. Richie DL, et al. Among authors: tao j. Antimicrob Agents Chemother. 2013 May;57(5):2272-80. doi: 10.1128/AAC.01809-12. Epub 2013 Mar 11. Antimicrob Agents Chemother. 2013. PMID: 23478965 Free PMC article.
An integrated approach for identification and target validation of antifungal compounds active against Erg11p.
Hoepfner D, Karkare S, Helliwell SB, Pfeifer M, Trunzer M, De Bonnechose S, Zimmerlin A, Tao J, Richie D, Hofmann A, Reinker S, Frederiksen M, Movva NR, Porter JA, Ryder NS, Parker CN. Hoepfner D, et al. Among authors: tao j. Antimicrob Agents Chemother. 2012 Aug;56(8):4233-40. doi: 10.1128/AAC.06332-11. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615293 Free PMC article.
Dark chemical matter as a promising starting point for drug lead discovery.
Wassermann AM, Lounkine E, Hoepfner D, Le Goff G, King FJ, Studer C, Peltier JM, Grippo ML, Prindle V, Tao J, Schuffenhauer A, Wallace IM, Chen S, Krastel P, Cobos-Correa A, Parker CN, Davies JW, Glick M. Wassermann AM, et al. Among authors: tao j. Nat Chem Biol. 2015 Dec;11(12):958-66. doi: 10.1038/nchembio.1936. Epub 2015 Oct 19. Nat Chem Biol. 2015. PMID: 26479441
The mevalonate pathway of Staphylococcus aureus.
Balibar CJ, Shen X, Tao J. Balibar CJ, et al. Among authors: tao j. J Bacteriol. 2009 Feb;191(3):851-61. doi: 10.1128/JB.01357-08. Epub 2008 Nov 21. J Bacteriol. 2009. PMID: 19028897 Free PMC article.
5,924 results