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Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade a and clade B v3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking.
Krachmarov C, Pinter A, Honnen WJ, Gorny MK, Nyambi PN, Zolla-Pazner S, Kayman SC. Krachmarov C, et al. Among authors: pinter a. J Virol. 2005 Jan;79(2):780-90. doi: 10.1128/JVI.79.2.780-790.2005. J Virol. 2005. PMID: 15613306 Free PMC article.
Characterization of structural features and diversity of variable-region determinants of related quaternary epitopes recognized by human and rhesus macaque monoclonal antibodies possessing unusually potent neutralizing activities.
Krachmarov C, Lai Z, Honnen WJ, Salomon A, Gorny MK, Zolla-Pazner S, Robinson J, Pinter A. Krachmarov C, et al. Among authors: pinter a. J Virol. 2011 Oct;85(20):10730-40. doi: 10.1128/JVI.00365-11. Epub 2011 Aug 10. J Virol. 2011. PMID: 21835798 Free PMC article.
Specific sequences commonly found in the V3 domain of HIV-1 subtype C isolates affect the overall conformation of native Env and induce a neutralization-resistant phenotype independent of V1/V2 masking.
Salomon A, Krachmarov C, Lai Z, Honnen W, Zingman BS, Sarlo J, Gorny MK, Zolla-Pazner S, Robinson JE, Pinter A. Salomon A, et al. Among authors: pinter a. Virology. 2014 Jan 5;448:363-74. doi: 10.1016/j.virol.2013.10.007. Epub 2013 Nov 12. Virology. 2014. PMID: 24314667 Free PMC article.
668 results