Dolezal O - Search Results

1

A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo.

Dransfield DT, Cohen EH, Chang Q, Sparrow LG, Bentley JD, Dolezal O, Xiao X, Peat TS, Newman J, Pilling PA, Phan T, Priebe I, Brierley GV, Kastrapeli N, Kopacz K, Martik D, Wassaf D, Rank D, Conley G, Huang Y, Adams TE, Cosgrove L. Dransfield DT, et al. Among authors: dolezal o. Mol Cancer Ther. 2010 Jun;9(6):1809-19. doi: 10.1158/1535-7163.MCT-09-1134. Epub 2010 Jun 1. Mol Cancer Ther. 2010. PMID: 20515953

2

Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by Sortase A-mediated protein ligation.

Madej MP, Coia G, Williams CC, Caine JM, Pearce LA, Attwood R, Bartone NA, Dolezal O, Nisbet RM, Nuttall SD, Adams TE. Madej MP, et al. Among authors: dolezal o. Biotechnol Bioeng. 2012 Jun;109(6):1461-70. doi: 10.1002/bit.24407. Epub 2011 Dec 26. Biotechnol Bioeng. 2012. PMID: 22170409

3

The DINGO dataset: a comprehensive set of data for the SAMPL challenge.

Newman J, Dolezal O, Fazio V, Caradoc-Davies T, Peat TS. Newman J, et al. Among authors: dolezal o. J Comput Aided Mol Des. 2012 May;26(5):497-503. doi: 10.1007/s10822-011-9521-2. Epub 2011 Dec 21. J Comput Aided Mol Des. 2012. PMID: 22187139 Free PMC article.

4

A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.

Koziolek EJ, Donoghue JF, Bentley JD, Lovrecz G, Dolezal O, Ward CW, Rothacker J, Nice EC, Burgess AW, Hafner M, Johns TG, Adams TE. Koziolek EJ, et al. Among authors: dolezal o. Growth Factors. 2012 Oct;30(5):310-9. doi: 10.3109/08977194.2012.709516. Epub 2012 Aug 2. Growth Factors. 2012. PMID: 22856597

5

Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.

Epa VC, Dolezal O, Doughty L, Xiao X, Jost C, Plückthun A, Adams TE. Epa VC, et al. Among authors: dolezal o. PLoS One. 2013;8(3):e59163. doi: 10.1371/journal.pone.0059163. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527120 Free PMC article.

6

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK.

Chhabra S, Barlow N, Dolezal O, Hattarki MK, Newman J, Peat TS, Graham B, Swarbrick JD. Chhabra S, et al. Among authors: dolezal o. PLoS One. 2013;8(4):e59535. doi: 10.1371/journal.pone.0059535. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565155 Free PMC article.

7

Interrogating HIV integrase for compounds that bind--a SAMPL challenge.

Peat TS, Dolezal O, Newman J, Mobley D, Deadman JJ. Peat TS, et al. Among authors: dolezal o. J Comput Aided Mol Des. 2014 Apr;28(4):347-62. doi: 10.1007/s10822-014-9721-7. Epub 2014 Feb 16. J Comput Aided Mol Des. 2014. PMID: 24532034 Free PMC article.

8

Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination.

Woods LA, Dolezal O, Ren B, Ryan JH, Peat TS, Poulsen SA. Woods LA, et al. Among authors: dolezal o. J Med Chem. 2016 Mar 10;59(5):2192-204. doi: 10.1021/acs.jmedchem.5b01940. Epub 2016 Feb 29. J Med Chem. 2016. PMID: 26882437

9

Identification of a New Zinc Binding Chemotype by Fragment Screening.

Chrysanthopoulos PK, Mujumdar P, Woods LA, Dolezal O, Ren B, Peat TS, Poulsen SA. Chrysanthopoulos PK, et al. Among authors: dolezal o. J Med Chem. 2017 Sep 14;60(17):7333-7349. doi: 10.1021/acs.jmedchem.7b00606. Epub 2017 Sep 1. J Med Chem. 2017. PMID: 28817930

10

APOMAB Antibody-Drug Conjugates Targeting Dead Tumor Cells are Effective In Vivo.

Staudacher AH, Li Y, Liapis V, Hou JJC, Chin D, Dolezal O, Adams TE, van Berkel PH, Brown MP. Staudacher AH, et al. Among authors: dolezal o. Mol Cancer Ther. 2019 Feb;18(2):335-345. doi: 10.1158/1535-7163.MCT-18-0842. Epub 2018 Nov 9. Mol Cancer Ther. 2019. PMID: 30413648

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