Fox EM - Search Results

1

Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.

Miller TW, Hennessy BT, González-Angulo AM, Fox EM, Mills GB, Chen H, Higham C, García-Echeverría C, Shyr Y, Arteaga CL. Miller TW, et al. Among authors: fox em. J Clin Invest. 2010 Jul;120(7):2406-13. doi: 10.1172/JCI41680. Epub 2010 Jun 7. J Clin Invest. 2010. PMID: 20530877 Free PMC article.

2

A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer.

Fox EM, Miller TW, Balko JM, Kuba MG, Sánchez V, Smith RA, Liu S, González-Angulo AM, Mills GB, Ye F, Shyr Y, Manning HC, Buck E, Arteaga CL. Fox EM, et al. Cancer Res. 2011 Nov 1;71(21):6773-84. doi: 10.1158/0008-5472.CAN-11-1295. Epub 2011 Sep 9. Cancer Res. 2011. PMID: 21908557 Free PMC article.

3

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer.

Miller TW, Balko JM, Fox EM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, Jiang A, Smith RA, Maira SM, Manning HC, González-Angulo AM, Mills GB, Higham C, Chanthaphaychith S, Kuba MG, Miller WR, Shyr Y, Arteaga CL. Miller TW, et al. Among authors: fox em. Cancer Discov. 2011 Sep;1(4):338-51. doi: 10.1158/2159-8290.CD-11-0101. Epub 2011 Jul 20. Cancer Discov. 2011. PMID: 22049316 Free PMC article.

4

LYN-activating mutations mediate antiestrogen resistance in estrogen receptor-positive breast cancer.

Schwarz LJ, Fox EM, Balko JM, Garrett JT, Kuba MG, Estrada MV, González-Angulo AM, Mills GB, Red-Brewer M, Mayer IA, Abramson V, Rizzo M, Kelley MC, Meszoely IM, Arteaga CL. Schwarz LJ, et al. Among authors: fox em. J Clin Invest. 2014 Dec;124(12):5490-502. doi: 10.1172/JCI72573. Epub 2014 Nov 17. J Clin Invest. 2014. PMID: 25401474 Free PMC article. Clinical Trial.

5

Abrogating endocrine resistance by targeting ERα and PI3K in breast cancer.

Fox EM, Arteaga CL, Miller TW. Fox EM, et al. Front Oncol. 2012 Oct 16;2:145. doi: 10.3389/fonc.2012.00145. eCollection 2012. Front Oncol. 2012. PMID: 23087906 Free PMC article.

6

Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation.

Fox EM, Kuba MG, Miller TW, Davies BR, Arteaga CL. Fox EM, et al. Breast Cancer Res. 2013;15(4):R55. doi: 10.1186/bcr3449. Breast Cancer Res. 2013. PMID: 23844554 Free PMC article.

7

Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.

Fox EM, Bernaciak TM, Wen J, Weaver AM, Shupnik MA, Silva CM. Fox EM, et al. Mol Endocrinol. 2008 Aug;22(8):1781-96. doi: 10.1210/me.2007-0419. Epub 2008 Jun 11. Mol Endocrinol. 2008. PMID: 18550772 Free PMC article.

8

Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells.

Boerner JL, Gibson MA, Fox EM, Posner ED, Parsons SJ, Silva CM, Shupnik MA. Boerner JL, et al. Among authors: fox em. Mol Endocrinol. 2005 Nov;19(11):2660-70. doi: 10.1210/me.2004-0439. Epub 2005 Jun 23. Mol Endocrinol. 2005. PMID: 15976008

9

ERbeta in breast cancer--onlooker, passive player, or active protector?

Fox EM, Davis RJ, Shupnik MA. Fox EM, et al. Steroids. 2008 Oct;73(11):1039-51. doi: 10.1016/j.steroids.2008.04.006. Epub 2008 Apr 20. Steroids. 2008. PMID: 18501937 Free PMC article. Review.

10

Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways.

Fox EM, Andrade J, Shupnik MA. Fox EM, et al. Steroids. 2009 Jul;74(7):622-7. doi: 10.1016/j.steroids.2008.10.014. Epub 2008 Nov 5. Steroids. 2009. PMID: 18996136 Free PMC article. Review.

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