Heldens JG - Search Results

1

Master donor viruses A/Leningrad/134/17/57 (H2N2) and B/USSR/60/69 and derived reassortants used in live attenuated influenza vaccine (LAIV) do not display neurovirulent properties in a mouse model.

Voeten JT, Kiseleva IV, Glansbeek HL, Basten SM, Drieszen-van der Cruijsen SK, Rudenko LG, van den Bosch H, Heldens JG. Voeten JT, et al. Among authors: heldens jg. Arch Virol. 2010 Sep;155(9):1391-9. doi: 10.1007/s00705-010-0719-8. Epub 2010 Jun 10. Arch Virol. 2010. PMID: 20532926 Free article.

2

Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2).

Isakova-Sivak I, Chen LM, Matsuoka Y, Voeten JT, Kiseleva I, Heldens JG, den Bosch Hv, Klimov A, Rudenko L, Cox NJ, Donis RO. Isakova-Sivak I, et al. Among authors: heldens jg. Virology. 2011 Apr 10;412(2):297-305. doi: 10.1016/j.virol.2011.01.004. Epub 2011 Feb 18. Virology. 2011. PMID: 21315402 Free article.

3

PB2 and PA genes control the expression of the temperature-sensitive phenotype of cold-adapted B/USSR/60/69 influenza master donor virus.

Kiseleva IV, Voeten JT, Teley LC, Larionova NV, Drieszen-van der Cruijsen SK, Basten SM, Heldens JG, van den Bosch H, Rudenko LG. Kiseleva IV, et al. Among authors: heldens jg. J Gen Virol. 2010 Apr;91(Pt 4):931-7. doi: 10.1099/vir.0.017996-0. Epub 2009 Dec 9. J Gen Virol. 2010. PMID: 20007357

4

Characterization of reverse genetics-derived cold-adapted master donor virus A/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model.

Isakova-Sivak I, Chen LM, Bourgeois M, Matsuoka Y, Voeten JT, Heldens JG, van den Bosch H, Klimov A, Rudenko L, Cox NJ, Donis RO. Isakova-Sivak I, et al. Among authors: heldens jg. Clin Vaccine Immunol. 2014 May;21(5):722-31. doi: 10.1128/CVI.00819-13. Epub 2014 Mar 19. Clin Vaccine Immunol. 2014. PMID: 24648485 Free PMC article.

5

Safety and immunogenicity in man of a cell culture derived trivalent live attenuated seasonal influenza vaccine: a Phase I dose escalating study in healthy volunteers.

Heldens J, Hulskotte E, Voeten T, Breedveld B, Verweij P, van Duijnhoven W, Rudenko L, van Damme P, van den Bosch H. Heldens J, et al. Vaccine. 2014 Sep 3;32(39):5118-24. doi: 10.1016/j.vaccine.2014.05.030. Epub 2014 May 23. Vaccine. 2014. PMID: 24858566 Clinical Trial.

6

[Leading role of genes coding polymerase complex in attenuation of domestic donor viruses for A and B live influenza vaccine].

Kiseleva IV, Larionova NV, Voeten JT, Teley LC, Drieszen-van der Cruijsen SK, Heldens JG, van den Bosch JF, Rudenko LG. Kiseleva IV, et al. Among authors: heldens jg. Zh Mikrobiol Epidemiol Immunobiol. 2010 Nov-Dec;(6):41-7. Zh Mikrobiol Epidemiol Immunobiol. 2010. PMID: 21381376 Russian.

7

[Genome composition analysis of the reassortant influenza viruses used in seasonal and pandemic live attenuated influenza vaccine].

Kiseleva IV, Voeten JT, Teley LC, Larionova NV, Dubrovina IA, Berdygulova ZhA, Bazhenova EA, van den Bosch H, Heldens JG, Rudenko LG. Kiseleva IV, et al. Among authors: heldens jg. Mol Gen Mikrobiol Virusol. 2011;(4):29-36. Mol Gen Mikrobiol Virusol. 2011. PMID: 22312898 Russian.

8

Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine.

Hagenaars N, Verheul RJ, Mooren I, de Jong PH, Mastrobattista E, Glansbeek HL, Heldens JG, van den Bosch H, Hennink WE, Jiskoot W. Hagenaars N, et al. Among authors: heldens jg. J Control Release. 2009 Dec 3;140(2):126-33. doi: 10.1016/j.jconrel.2009.08.018. Epub 2009 Aug 25. J Control Release. 2009. PMID: 19712713

9

Comparative immunogenicity and cross-clade protective efficacy of mammalian cell-grown inactivated and live attenuated H5N1 reassortant vaccines in ferrets.

Gustin KM, Maines TR, Belser JA, van Hoeven N, Lu X, Dong L, Isakova-Sivak I, Chen LM, Voeten JT, Heldens JG, van den Bosch H, Cox NJ, Tumpey TM, Klimov AI, Rudenko L, Donis RO, Katz JM. Gustin KM, et al. Among authors: heldens jg. J Infect Dis. 2011 Nov 15;204(10):1491-9. doi: 10.1093/infdis/jir596. Epub 2011 Sep 28. J Infect Dis. 2011. PMID: 21957153

10

Feasibility of single-shot H5N1 influenza vaccine in ferrets, macaques and rabbits.

Heldens JG, Glansbeek HL, Hilgers LA, Haenen B, Stittelaar KJ, Osterhaus AD, van den Bosch JF. Heldens JG, et al. Vaccine. 2010 Nov 29;28(51):8125-31. doi: 10.1016/j.vaccine.2010.09.097. Epub 2010 Oct 13. Vaccine. 2010. PMID: 20950729

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