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A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.
Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, Li J, Lu B, Chavan S, Rosas-Ballina M, Al-Abed Y, Akira S, Bierhaus A, Erlandsson-Harris H, Andersson U, Tracey KJ. Yang H, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11942-7. doi: 10.1073/pnas.1003893107. Epub 2010 Jun 14. Proc Natl Acad Sci U S A. 2010. PMID: 20547845 Free PMC article.
Activation of innate immunity by 14-3-3 ε, a new potential alarmin in osteoarthritis.
Millerand M, Sudre L, Nefla M, Pène F, Rousseau C, Pons A, Ravat A, André-Leroux G, Akira S, Satoh T, Berenbaum F, Jacques C. Millerand M, et al. Among authors: akira s. Osteoarthritis Cartilage. 2020 May;28(5):646-657. doi: 10.1016/j.joca.2020.03.002. Epub 2020 Mar 12. Osteoarthritis Cartilage. 2020. PMID: 32173627 Free article.
Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis.
Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, Iovanna J, Simonet M, Chamaillard M. Dessein R, et al. Among authors: akira s. Gut. 2009 Jun;58(6):771-6. doi: 10.1136/gut.2008.168443. Epub 2009 Jan 27. Gut. 2009. PMID: 19174417
1,324 results