Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA.
Huang H, Wang H, Lloyd RS, Rizzo CJ, Stone MP.
Huang H, et al.
Chem Res Toxicol. 2009 Jan;22(1):187-200. doi: 10.1021/tx800320m.
Chem Res Toxicol. 2009.
PMID: 19053179
Free PMC article.
This was in contrast to when this adduct was correctly paired with dCyd, conditions under which it underwent ring opening and rearrangement to diastereomeric minor groove cyclic hemiacetals [ Huang , H. , Wang , H. , Qi , N. , Lloyd , R. S. , Harris , T. M. , …
This was in contrast to when this adduct was correctly paired with dCyd, conditions under which it underwent ring opening and rearrangement …