Huber R - Search Results

1

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.

Krojer T, Sawa J, Huber R, Clausen T. Krojer T, et al. Among authors: huber r. Nat Struct Mol Biol. 2010 Jul;17(7):844-52. doi: 10.1038/nsmb.1840. Epub 2010 Jun 27. Nat Struct Mol Biol. 2010. PMID: 20581825

2

Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins.

Krojer T, Pangerl K, Kurt J, Sawa J, Stingl C, Mechtler K, Huber R, Ehrmann M, Clausen T. Krojer T, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7702-7. doi: 10.1073/pnas.0803392105. Epub 2008 May 27. Proc Natl Acad Sci U S A. 2008. PMID: 18505836 Free PMC article.

3

HTRA proteases: regulated proteolysis in protein quality control.

Clausen T, Kaiser M, Huber R, Ehrmann M. Clausen T, et al. Among authors: huber r. Nat Rev Mol Cell Biol. 2011 Mar;12(3):152-62. doi: 10.1038/nrm3065. Epub 2011 Feb 16. Nat Rev Mol Cell Biol. 2011. PMID: 21326199 Review.

4

Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.

Krojer T, Garrido-Franco M, Huber R, Ehrmann M, Clausen T. Krojer T, et al. Among authors: huber r. Nature. 2002 Mar 28;416(6879):455-9. doi: 10.1038/416455a. Nature. 2002. PMID: 11919638

5

Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli.

Meltzer M, Hasenbein S, Mamant N, Merdanovic M, Poepsel S, Hauske P, Kaiser M, Huber R, Krojer T, Clausen T, Ehrmann M. Meltzer M, et al. Among authors: huber r. Res Microbiol. 2009 Nov;160(9):660-6. doi: 10.1016/j.resmic.2009.07.012. Epub 2009 Aug 18. Res Microbiol. 2009. PMID: 19695325 Free article. Review.

6

Conversion of a regulatory into a degradative protease.

Hasenbein S, Meltzer M, Hauske P, Kaiser M, Huber R, Clausen T, Ehrmann M. Hasenbein S, et al. Among authors: huber r. J Mol Biol. 2010 Apr 9;397(4):957-66. doi: 10.1016/j.jmb.2010.02.027. Epub 2010 Feb 22. J Mol Biol. 2010. PMID: 20184896

7

Activation by substoichiometric inhibition.

Merdanovic M, Burston SG, Schmitz AL, Köcher S, Knapp S, Clausen T, Kaiser M, Huber R, Ehrmann M. Merdanovic M, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1414-1418. doi: 10.1073/pnas.1918721117. Epub 2020 Jan 6. Proc Natl Acad Sci U S A. 2020. PMID: 31907318 Free PMC article.

8

Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.

Breithaupt C, Kurzbauer R, Schaller F, Stintzi A, Schaller A, Huber R, Macheroux P, Clausen T. Breithaupt C, et al. Among authors: huber r. J Mol Biol. 2009 Oct 9;392(5):1266-77. doi: 10.1016/j.jmb.2009.07.087. Epub 2009 Aug 4. J Mol Biol. 2009. PMID: 19660473

9

Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis.

Garrido-Franco M, Laber B, Huber R, Clausen T. Garrido-Franco M, et al. Among authors: huber r. J Mol Biol. 2002 Aug 23;321(4):601-12. doi: 10.1016/s0022-2836(02)00695-2. J Mol Biol. 2002. PMID: 12206776

10

Molecular machines for protein degradation.

Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R. Groll M, et al. Among authors: huber r. Chembiochem. 2005 Feb;6(2):222-56. doi: 10.1002/cbic.200400313. Chembiochem. 2005. PMID: 15678420 Review.

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