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Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide.
Mizutani H, Tada-Oikawa S, Hiraku Y, Kojima M, Kawanishi S. Mizutani H, et al. Life Sci. 2005 Feb 11;76(13):1439-53. doi: 10.1016/j.lfs.2004.05.040. Epub 2005 Jan 20. Life Sci. 2005. PMID: 15680309
Our previous study has demonstrated that TAS-103, a topoisomerase inhibitor, induces apoptosis through DNA cleavage and subsequent H(2)O(2) generation mediated by NAD(P)H oxidase activation [H. Mizutani et al. J. Biol. Chem. 277 (2002) 30684-30689]. Th …
Our previous study has demonstrated that TAS-103, a topoisomerase inhibitor, induces apoptosis through DNA cleavage and subsequent H( …
786 results