de Graaf IA - Search Results

1

Reduced ischemia-reoxygenation injury in rat intestine after luminal preservation with a tailored solution.

Roskott AM, Nieuwenhuijs VB, Leuvenink HG, Dijkstra G, Ottens P, de Jager MH, Gonalves Dias Pereira P, Fidler V, Groothuis GM, Ploeg RJ, de Graaf IA. Roskott AM, et al. Among authors: de jager mh, de graaf ia. Transplantation. 2010 Sep 27;90(6):622-9. doi: 10.1097/TP.0b013e3181ebf796. Transplantation. 2010. PMID: 20689496 Free article.

2

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies.

de Graaf IA, Olinga P, de Jager MH, Merema MT, de Kanter R, van de Kerkhof EG, Groothuis GM. de Graaf IA, et al. Among authors: de jager mh, de kanter r. Nat Protoc. 2010 Sep;5(9):1540-51. doi: 10.1038/nprot.2010.111. Epub 2010 Aug 19. Nat Protoc. 2010. PMID: 20725069

3

Precision-cut intestinal slices as in vitro tool for studies on drug metabolism.

Groothuis GM, de Graaf IA. Groothuis GM, et al. Among authors: de graaf ia. Curr Drug Metab. 2013 Jan;14(1):112-9. Curr Drug Metab. 2013. PMID: 22497569 Review.

4

Evaluation of the intestinal toxicity and transport of xenobiotics utilizing precision-cut slices.

Niu X, de Graaf IA, Groothuis GM. Niu X, et al. Among authors: de graaf ia. Xenobiotica. 2013 Jan;43(1):73-83. doi: 10.3109/00498254.2012.729870. Epub 2012 Oct 30. Xenobiotica. 2013. PMID: 23106567 Review.

5

Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.

Li M, de Graaf IA, de Jager MH, Groothuis GM. Li M, et al. Among authors: de jager mh, de graaf ia. Toxicol In Vitro. 2015 Aug;29(5):1070-8. doi: 10.1016/j.tiv.2015.04.011. Epub 2015 Apr 25. Toxicol In Vitro. 2015. PMID: 25917215

6

Precision-cut intestinal slices: alternative model for drug transport, metabolism, and toxicology research.

Li M, de Graaf IA, Groothuis GM. Li M, et al. Among authors: de graaf ia. Expert Opin Drug Metab Toxicol. 2016;12(2):175-90. doi: 10.1517/17425255.2016.1125882. Epub 2016 Jan 9. Expert Opin Drug Metab Toxicol. 2016. PMID: 26750630 Free article. Review.

7

Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.

van de Kerkhof EG, de Graaf IA, de Jager MH, Meijer DK, Groothuis GM. van de Kerkhof EG, et al. Among authors: de jager mh, de graaf ia. Drug Metab Dispos. 2005 Nov;33(11):1613-20. doi: 10.1124/dmd.105.005686. Epub 2005 Jul 28. Drug Metab Dispos. 2005. PMID: 16051733

8

In vitro methods to study intestinal drug metabolism.

van de Kerkhof EG, de Graaf IA, Groothuis GM. van de Kerkhof EG, et al. Among authors: de graaf ia. Curr Drug Metab. 2007 Oct;8(7):658-75. doi: 10.2174/138920007782109742. Curr Drug Metab. 2007. PMID: 17979654 Review.

9

Analysis of gene expression changes to elucidate the mechanism of chilling injury in precision-cut liver slices.

Guan N, Blomsma SA, Fahy GM, Groothuis GM, de Graaf IA. Guan N, et al. Among authors: de graaf ia. Toxicol In Vitro. 2013 Mar;27(2):890-9. doi: 10.1016/j.tiv.2012.10.009. Epub 2012 Oct 27. Toxicol In Vitro. 2013. PMID: 23111282

10

Nanoparticle formulation of a poorly soluble cannabinoid receptor 1 antagonist improves absorption by rat and human intestine.

Siissalo S, de Waard H, de Jager MH, Hayeshi R, Frijlink HW, Hinrichs WL, Dinter-Heidorn H, van Dam A, Proost JH, Groothuis GM, de Graaf IA. Siissalo S, et al. Among authors: de jager mh, de graaf ia, de waard h. Drug Metab Dispos. 2013 Aug;41(8):1557-65. doi: 10.1124/dmd.112.049585. Epub 2013 Jun 3. Drug Metab Dispos. 2013. PMID: 23733277

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