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Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.
Brancati F, Fortugno P, Bottillo I, Lopez M, Josselin E, Boudghene-Stambouli O, Agolini E, Bernardini L, Bellacchio E, Iannicelli M, Rossi A, Dib-Lachachi A, Stuppia L, Palka G, Mundlos S, Stricker S, Kornak U, Zambruno G, Dallapiccola B. Brancati F, et al. Among authors: lopez m. Am J Hum Genet. 2010 Aug 13;87(2):265-73. doi: 10.1016/j.ajhg.2010.07.003. Am J Hum Genet. 2010. PMID: 20691405 Free PMC article.
Nectin-4 mutations causing ectodermal dysplasia with syndactyly perturb the rac1 pathway and the kinetics of adherens junction formation.
Fortugno P, Josselin E, Tsiakas K, Agolini E, Cestra G, Teson M, Santer R, Castiglia D, Novelli G, Dallapiccola B, Kurth I, Lopez M, Zambruno G, Brancati F. Fortugno P, et al. Among authors: lopez m. J Invest Dermatol. 2014 Aug;134(8):2146-2153. doi: 10.1038/jid.2014.119. Epub 2014 Feb 27. J Invest Dermatol. 2014. PMID: 24577405 Free article.
Adherens junction protein nectin-4 is the epithelial receptor for measles virus.
Mühlebach MD, Mateo M, Sinn PL, Prüfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB Jr, Cichutek K, von Messling V, Lopez M, Cattaneo R. Mühlebach MD, et al. Among authors: lopez m. Nature. 2011 Nov 2;480(7378):530-3. doi: 10.1038/nature10639. Nature. 2011. PMID: 22048310 Free PMC article.
Nectin-4 is a new histological and serological tumor associated marker for breast cancer.
Fabre-Lafay S, Monville F, Garrido-Urbani S, Berruyer-Pouyet C, Ginestier C, Reymond N, Finetti P, Sauvan R, Adélaïde J, Geneix J, Lecocq E, Popovici C, Dubreuil P, Viens P, Gonçalves A, Charafe-Jauffret E, Jacquemier J, Birnbaum D, Lopez M. Fabre-Lafay S, et al. Among authors: lopez m. BMC Cancer. 2007 May 2;7:73. doi: 10.1186/1471-2407-7-73. BMC Cancer. 2007. PMID: 17474988 Free PMC article.
[Triple-negative breast cancer therapy via nectin-4 targeting].
M-Rabet M, Bertucci F, Birnbaum D, Lopez M. M-Rabet M, et al. Among authors: lopez m. Med Sci (Paris). 2017 Nov;33(11):936-939. doi: 10.1051/medsci/20173311007. Epub 2017 Dec 4. Med Sci (Paris). 2017. PMID: 29200388 Free article. French. No abstract available.
7,273 results