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Pictet-Spengler based synthesis of a bisarylmaleimide glycogen synthase kinase-3 inhibitor.
Org Lett. 2010 Aug 20;12(16):3700-3. doi: 10.1021/ol101405g.
Org Lett. 2010.
PMID: 20704418
Additives promote Noyori-type reductions of a β-keto-γ-lactam: asymmetric syntheses of serotonin norepinephrine reuptake inhibitors.
Magnus NA, Astleford BA, Laird DL, Maloney TD, McFarland AD, Rizzo JR, Ruble JC, Stephenson GA, Wepsiec JP.
Magnus NA, et al. Among authors: wepsiec jp.
J Org Chem. 2013 Jun 7;78(11):5768-74. doi: 10.1021/jo400589j. Epub 2013 May 20.
J Org Chem. 2013.
PMID: 23650960
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Resolution of delta-Lactams Provides Access to Nonracemic Benzoquinolinones: The Synthesis of LY300502 and LY300503.
Astleford BA, Audia JE, Deeter J, Heath PC, Janisse SK, Kress TJ, Wepsiec JP, Weigel LO.
Astleford BA, et al. Among authors: wepsiec jp.
J Org Chem. 1996 Jun 26;61(13):4450-4454. doi: 10.1021/jo9601425.
J Org Chem. 1996.
PMID: 11667351
No abstract available.
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Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors.
Monn JA, Valli MJ, Massey SM, Hansen MM, Kress TJ, Wepsiec JP, Harkness AR, Grutsch JL Jr, Wright RA, Johnson BG, Andis SL, Kingston A, Tomlinson R, Lewis R, Griffey KR, Tizzano JP, Schoepp DD.
Monn JA, et al. Among authors: wepsiec jp.
J Med Chem. 1999 Mar 25;42(6):1027-40. doi: 10.1021/jm980616n.
J Med Chem. 1999.
PMID: 10090786
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