Westrop GD - Search Results

1

α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.

Steert K, Berg M, Mottram JC, Westrop GD, Coombs GH, Cos P, Maes L, Joossens J, Van der Veken P, Haemers A, Augustyns K. Steert K, et al. Among authors: westrop gd. ChemMedChem. 2010 Oct 4;5(10):1734-48. doi: 10.1002/cmdc.201000265. ChemMedChem. 2010. PMID: 20799311 Free PMC article.

2

Dipeptidyl alpha-fluorovinyl Michael acceptors: synthesis and activity against cysteine proteases.

Steert K, El-Sayed I, Van der Veken P, Krishtal A, Van Alsenoy C, Westrop GD, Mottram JC, Coombs GH, Augustyns K, Haemers A. Steert K, et al. Among authors: westrop gd. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6563-6. doi: 10.1016/j.bmcl.2007.09.075. Epub 2007 Oct 23. Bioorg Med Chem Lett. 2007. PMID: 17936625

3

The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors.

Smith BO, Picken NC, Westrop GD, Bromek K, Mottram JC, Coombs GH. Smith BO, et al. Among authors: westrop gd. J Biol Chem. 2006 Mar 3;281(9):5821-8. doi: 10.1074/jbc.M510868200. Epub 2005 Dec 28. J Biol Chem. 2006. PMID: 16407198 Free PMC article.

4

Chemical shift assignments of Leishmania mexicana ICP, a novel cysteine peptidase inhibitor.

Smith BO, Westrop GD, Mottram JC, Coombs GH. Smith BO, et al. Among authors: westrop gd. J Biomol NMR. 2006;36 Suppl 1(Suppl 1):7. doi: 10.1007/s10858-005-4739-8. J Biomol NMR. 2006. PMID: 16596344 Free PMC article. No abstract available.

5

Structure of Leishmania major cysteine synthase.

Fyfe PK, Westrop GD, Ramos T, Müller S, Coombs GH, Hunter WN. Fyfe PK, et al. Among authors: westrop gd. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):738-43. doi: 10.1107/S1744309112019124. Epub 2012 Jun 22. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22750854 Free PMC article.

6

The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element.

Brooks DR, Denise H, Westrop GD, Coombs GH, Mottram JC. Brooks DR, et al. Among authors: westrop gd. J Biol Chem. 2001 Dec 14;276(50):47061-9. doi: 10.1074/jbc.M108498200. Epub 2001 Oct 9. J Biol Chem. 2001. PMID: 11592967 Free article.

7

Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens.

Sanderson SJ, Westrop GD, Scharfstein J, Mottram JC, Coombs GH. Sanderson SJ, et al. Among authors: westrop gd. FEBS Lett. 2003 May 8;542(1-3):12-6. doi: 10.1016/s0014-5793(03)00327-2. FEBS Lett. 2003. PMID: 12729889 Free article.

8

Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing.

Moss CX, Westrop GD, Juliano L, Coombs GH, Mottram JC. Moss CX, et al. Among authors: westrop gd. FEBS Lett. 2007 Dec 11;581(29):5635-9. doi: 10.1016/j.febslet.2007.11.009. Epub 2007 Nov 20. FEBS Lett. 2007. PMID: 18005666 Free article.

9

Two pathways for cysteine biosynthesis in Leishmania major.

Williams RA, Westrop GD, Coombs GH. Williams RA, et al. Among authors: westrop gd. Biochem J. 2009 May 27;420(3):451-62. doi: 10.1042/BJ20082441. Biochem J. 2009. PMID: 19296828

10

Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8.

Judice WA, Manfredi MA, Souza GP, Sansevero TM, Almeida PC, Shida CS, Gesteira TF, Juliano L, Westrop GD, Sanderson SJ, Coombs GH, Tersariol IL. Judice WA, et al. Among authors: westrop gd. PLoS One. 2013 Nov 21;8(11):e80153. doi: 10.1371/journal.pone.0080153. eCollection 2013. PLoS One. 2013. PMID: 24278253 Free PMC article.

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