Keeshan K - Search Results

1

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.

Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS. Keeshan K, et al. Blood. 2010 Dec 2;116(23):4948-57. doi: 10.1182/blood-2009-10-247361. Epub 2010 Aug 30. Blood. 2010. PMID: 20805362 Free PMC article.

2

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.

Dedhia PH, Keeshan K, Uljon S, Xu L, Vega ME, Shestova O, Zaks-Zilberman M, Romany C, Blacklow SC, Pear WS. Dedhia PH, et al. Among authors: keeshan k. Blood. 2010 Aug 26;116(8):1321-8. doi: 10.1182/blood-2009-07-229450. Epub 2010 Apr 21. Blood. 2010. PMID: 20410507 Free PMC article.

3

Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia.

Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS. Keeshan K, et al. Cancer Cell. 2006 Nov;10(5):401-11. doi: 10.1016/j.ccr.2006.09.012. Cancer Cell. 2006. PMID: 17097562 Free PMC article.

4

Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia.

Keeshan K, Shestova O, Ussin L, Pear WS. Keeshan K, et al. Blood Cells Mol Dis. 2008 Jan-Feb;40(1):119-21. doi: 10.1016/j.bcmd.2007.06.005. Epub 2007 Nov 7. Blood Cells Mol Dis. 2008. PMID: 17988908

5

The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.

Chen YX, Yan J, Keeshan K, Tubbs AT, Wang H, Silva A, Brown EJ, Hess JL, Pear WS, Hua X. Chen YX, et al. Among authors: keeshan k. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1018-23. doi: 10.1073/pnas.0510347103. Epub 2006 Jan 13. Proc Natl Acad Sci U S A. 2006. PMID: 16415155 Free PMC article.

6

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS. Maillard I, et al. Among authors: keeshan k. J Exp Med. 2006 Oct 2;203(10):2239-45. doi: 10.1084/jem.20061020. Epub 2006 Sep 11. J Exp Med. 2006. PMID: 16966428 Free PMC article.

7

Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation.

Rishi L, Hannon M, Salomè M, Hasemann M, Frank AK, Campos J, Timoney J, O'Connor C, Cahill MR, Porse B, Keeshan K. Rishi L, et al. Among authors: keeshan k. Blood. 2014 Apr 10;123(15):2389-400. doi: 10.1182/blood-2013-07-511683. Epub 2014 Feb 10. Blood. 2014. PMID: 24516045 Free article.

8

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.

Wouters BJ, Jordà MA, Keeshan K, Louwers I, Erpelinck-Verschueren CA, Tielemans D, Langerak AW, He Y, Yashiro-Ohtani Y, Zhang P, Hetherington CJ, Verhaak RG, Valk PJ, Löwenberg B, Tenen DG, Pear WS, Delwel R. Wouters BJ, et al. Among authors: keeshan k. Blood. 2007 Nov 15;110(10):3706-14. doi: 10.1182/blood-2007-02-073486. Epub 2007 Aug 1. Blood. 2007. PMID: 17671232 Free PMC article.

9

Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha.

Ferrari-Amorotti G, Keeshan K, Zattoni M, Guerzoni C, Iotti G, Cattelani S, Donato NJ, Calabretta B. Ferrari-Amorotti G, et al. Among authors: keeshan k. Blood. 2006 Aug 15;108(4):1353-62. doi: 10.1182/blood-2006-01-011833. Epub 2006 May 2. Blood. 2006. PMID: 16670262 Free PMC article.

10

Tribbles in acute leukemia.

Liang KL, Rishi L, Keeshan K. Liang KL, et al. Among authors: keeshan k. Blood. 2013 May 23;121(21):4265-70. doi: 10.1182/blood-2012-12-471300. Epub 2013 Apr 2. Blood. 2013. PMID: 23550039 Free article. Review.

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