Sagawa S - Search Results

1

Discovery of pyrrolopyridazines as novel DGAT1 inhibitors.

Fox BM, Iio K, Li K, Choi R, Inaba T, Jackson S, Sagawa S, Shan B, Tanaka M, Yoshida A, Kayser F. Fox BM, et al. Among authors: sagawa s. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6030-3. doi: 10.1016/j.bmcl.2010.08.066. Epub 2010 Aug 18. Bioorg Med Chem Lett. 2010. PMID: 20833038

2

Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.

Fox BM, Sugimoto K, Iio K, Yoshida A, Zhang JK, Li K, Hao X, Labelle M, Smith ML, Rubenstein SM, Ye G, McMinn D, Jackson S, Choi R, Shan B, Ma J, Miao S, Matsui T, Ogawa N, Suzuki M, Kobayashi A, Ozeki H, Okuma C, Ishii Y, Tomimoto D, Furakawa N, Tanaka M, Matsushita M, Takahashi M, Inaba T, Sagawa S, Kayser F. Fox BM, et al. Among authors: sagawa s. J Med Chem. 2014 Apr 24;57(8):3464-83. doi: 10.1021/jm500135c. Epub 2014 Apr 8. J Med Chem. 2014. PMID: 24670009

3

Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors.

Tanaka M, Sagawa S, Hoshi J, Shimoma F, Matsuda I, Sakoda K, Sasase T, Shindo M, Inaba T. Tanaka M, et al. Among authors: sagawa s. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5171-4. doi: 10.1016/j.bmcl.2004.07.061. Bioorg Med Chem Lett. 2004. PMID: 15380221

4

Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCbeta-selective inhibitors.

Tanaka M, Sagawa S, Hoshi J, Shimoma F, Yasue K, Ubukata M, Ikemoto T, Hase Y, Takahashi M, Sasase T, Ueda N, Matsushita M, Inaba T. Tanaka M, et al. Among authors: sagawa s. Bioorg Med Chem. 2006 Sep 1;14(17):5781-94. doi: 10.1016/j.bmc.2006.05.033. Epub 2006 Jun 9. Bioorg Med Chem. 2006. PMID: 16762554

5

Catalytic Asymmetric Aminolysis of 3,5,8-Trioxabicyclo[5.1.0]octane Providing an Optically Pure 2-Amino-1,3,4-butanetriol Equivalent.

Sagawa S, Abe H, Hase Y, Inaba T. Sagawa S, et al. J Org Chem. 1999 Jun 25;64(13):4962-4965. doi: 10.1021/jo9900883. J Org Chem. 1999. PMID: 11674582 No abstract available.

6

(1S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan+-4-yl][-2-hydroxyethylamm onium benzoate, a versatile building block for chiral 2-aminoalkanols: concise synthesis and application to nelfinavir, a potent HIV-protease inhibitor.

Inaba T, Yamada Y, Abe H, Sagawa S, Cho H. Inaba T, et al. Among authors: sagawa s. J Org Chem. 2000 Mar 24;65(6):1623-8. doi: 10.1021/jo991793e. J Org Chem. 2000. PMID: 10750488

7

Novel protein kinase C-beta isoform selective inhibitor JTT-010 ameliorates both hyper- and hypoalgesia in streptozotocin- induced diabetic rats.

Sasase T, Yamada H, Sakoda K, Imagawa N, Abe T, Ito M, Sagawa S, Tanaka M, Matsushita M. Sasase T, et al. Among authors: sagawa s. Diabetes Obes Metab. 2005 Sep;7(5):586-94. doi: 10.1111/j.1463-1326.2004.00447.x. Diabetes Obes Metab. 2005. PMID: 16050952

8

Treatment Strategies for Non-Small-Cell Lung Cancer with Comorbid Respiratory Disease; Interstitial Pneumonia, Chronic Obstructive Pulmonary Disease, and Tuberculosis.

Otoshi R, Ikeda S, Kaneko T, Sagawa S, Yamada C, Kumagai K, Moriuchi A, Sekine A, Baba T, Ogura T. Otoshi R, et al. Among authors: sagawa s. Cancers (Basel). 2024 Apr 29;16(9):1734. doi: 10.3390/cancers16091734. Cancers (Basel). 2024. PMID: 38730686 Free PMC article. Review.

9

KRAS^G12C Inhibitor as a Treatment Option for Non-Small-Cell Lung Cancer with Comorbid Interstitial Pneumonia.

Fujimoto K, Ikeda S, Tabata E, Kaneko T, Sagawa S, Yamada C, Kumagai K, Fukushima T, Haga S, Watanabe M, Muraoka T, Sekine A, Baba T, Ogura T. Fujimoto K, et al. Among authors: sagawa s. Cancers (Basel). 2024 Mar 28;16(7):1327. doi: 10.3390/cancers16071327. Cancers (Basel). 2024. PMID: 38611005 Free PMC article. Review.

10

Hypersensitivity pneumonitis with Paecilomyces as suspected inciting antigen.

Watanabe M, Okuda R, Ishida Y, Sagawa S, Muraoka T, Ikeda S, Sawazumi T, Takemura T, Hagiwara E, Ogura T. Watanabe M, et al. Among authors: sagawa s. Respir Med Case Rep. 2024 Mar 21;49:102013. doi: 10.1016/j.rmcr.2024.102013. eCollection 2024. Respir Med Case Rep. 2024. PMID: 38559328 Free PMC article.

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