Merbitz-Zahradnik T - Search Results

1

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.

Gremer L, Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, Zenker M, Wittinghofer A, Ahmadian MR. Gremer L, et al. Among authors: merbitz zahradnik t. Hum Mutat. 2011 Jan;32(1):33-43. doi: 10.1002/humu.21377. Epub 2010 Dec 9. Hum Mutat. 2011. PMID: 20949621 Free PMC article.

2

A restricted spectrum of NRAS mutations causes Noonan syndrome.

Cirstea IC, Kutsche K, Dvorsky R, Gremer L, Carta C, Horn D, Roberts AE, Lepri F, Merbitz-Zahradnik T, König R, Kratz CP, Pantaleoni F, Dentici ML, Joshi VA, Kucherlapati RS, Mazzanti L, Mundlos S, Patton MA, Silengo MC, Rossi C, Zampino G, Digilio C, Stuppia L, Seemanova E, Pennacchio LA, Gelb BD, Dallapiccola B, Wittinghofer A, Ahmadian MR, Tartaglia M, Zenker M. Cirstea IC, et al. Among authors: merbitz zahradnik t. Nat Genet. 2010 Jan;42(1):27-9. doi: 10.1038/ng.497. Epub 2009 Dec 6. Nat Genet. 2010. PMID: 19966803 Free PMC article.

3

Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation.

Gremer L, De Luca A, Merbitz-Zahradnik T, Dallapiccola B, Morlot S, Tartaglia M, Kutsche K, Ahmadian MR, Rosenberger G. Gremer L, et al. Among authors: merbitz zahradnik t. Hum Mol Genet. 2010 Mar 1;19(5):790-802. doi: 10.1093/hmg/ddp548. Epub 2009 Dec 8. Hum Mol Genet. 2010. PMID: 19995790

4

Molecular basis for atovaquone binding to the cytochrome bc1 complex.

Kessl JJ, Lange BB, Merbitz-Zahradnik T, Zwicker K, Hill P, Meunier B, Pálsdóttir H, Hunte C, Meshnick S, Trumpower BL. Kessl JJ, et al. Among authors: merbitz zahradnik t. J Biol Chem. 2003 Aug 15;278(33):31312-8. doi: 10.1074/jbc.M304042200. Epub 2003 Jun 5. J Biol Chem. 2003. PMID: 12791689 Free article.

5

Role of the Rieske iron-sulfur protein midpoint potential in the protonmotive Q-cycle mechanism of the cytochrome bc1 complex.

Snyder CH, Merbitz-Zahradnik T, Link TA, Trumpower BL. Snyder CH, et al. Among authors: merbitz zahradnik t. J Bioenerg Biomembr. 1999 Jun;31(3):235-42. doi: 10.1023/a:1005419712731. J Bioenerg Biomembr. 1999. PMID: 10591529 Review.

6

Failure to insert the iron-sulfur cluster into the Rieske iron-sulfur protein impairs both center N and center P of the cytochrome bc1 complex.

Gutierrez-Cirlos EB, Merbitz-Zahradnik T, Trumpower BL. Gutierrez-Cirlos EB, et al. Among authors: merbitz zahradnik t. J Biol Chem. 2002 Dec 27;277(52):50703-9. doi: 10.1074/jbc.M208556200. Epub 2002 Oct 10. J Biol Chem. 2002. PMID: 12377760 Free article.

7

Elimination of the disulfide bridge in the Rieske iron-sulfur protein allows assembly of the [2Fe-2S] cluster into the Rieske protein but damages the ubiquinol oxidation site in the cytochrome bc1 complex.

Merbitz-Zahradnik T, Zwicker K, Nett JH, Link TA, Trumpower BL. Merbitz-Zahradnik T, et al. Biochemistry. 2003 Nov 25;42(46):13637-45. doi: 10.1021/bi035344r. Biochemistry. 2003. PMID: 14622010

8

Inhibition of the yeast cytochrome bc1 complex by ilicicolin H, a novel inhibitor that acts at the Qn site of the bc1 complex.

Gutierrez-Cirlos EB, Merbitz-Zahradnik T, Trumpower BL. Gutierrez-Cirlos EB, et al. Among authors: merbitz zahradnik t. J Biol Chem. 2004 Mar 5;279(10):8708-14. doi: 10.1074/jbc.M311805200. Epub 2003 Dec 10. J Biol Chem. 2004. PMID: 14670947 Free article.

9

Alteration of the midpoint potential and catalytic activity of the rieske iron-sulfur protein by changes of amino acids forming hydrogen bonds to the iron-sulfur cluster.

Denke E, Merbitz-Zahradnik T, Hatzfeld OM, Snyder CH, Link TA, Trumpower BL. Denke E, et al. J Biol Chem. 1998 Apr 10;273(15):9085-93. doi: 10.1074/jbc.273.15.9085. J Biol Chem. 1998. PMID: 9535897 Free article.

10

Design of a ruthenium-labeled cytochrome c derivative to study electron transfer with the cytochrome bc1 complex.

Engstrom G, Rajagukguk R, Saunders AJ, Patel CN, Rajagukguk S, Merbitz-Zahradnik T, Xiao K, Pielak GJ, Trumpower B, Yu CA, Yu L, Durham B, Millett F. Engstrom G, et al. Among authors: merbitz zahradnik t. Biochemistry. 2003 Mar 18;42(10):2816-24. doi: 10.1021/bi027213g. Biochemistry. 2003. PMID: 12627947

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