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Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.
Fenouille N, Puissant A, Dufies M, Robert G, Jacquel A, Ohanna M, Deckert M, Pasquet JM, Mahon FX, Cassuto JP, Raynaud S, Tartare-Deckert S, Auberger P. Fenouille N, et al. Cancer Res. 2010 Dec 1;70(23):9659-70. doi: 10.1158/0008-5472.CAN-10-2034. Epub 2010 Nov 23. Cancer Res. 2010. PMID: 21098700
Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells.
Cheli Y, Giuliano S, Fenouille N, Allegra M, Hofman V, Hofman P, Bahadoran P, Lacour JP, Tartare-Deckert S, Bertolotto C, Ballotti R. Cheli Y, et al. Among authors: fenouille n. Oncogene. 2012 May 10;31(19):2461-70. doi: 10.1038/onc.2011.425. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996743
Mechanism of action of the multikinase inhibitor Foretinib.
Dufies M, Jacquel A, Robert G, Cluzeau T, Puissant A, Fenouille N, Legros L, Raynaud S, Cassuto JP, Luciano F, Auberger P. Dufies M, et al. Among authors: fenouille n. Cell Cycle. 2011 Dec 1;10(23):4138-48. doi: 10.4161/cc.10.23.18323. Epub 2011 Dec 1. Cell Cycle. 2011. PMID: 22101270
Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.
Puissant A, Dufies M, Fenouille N, Ben Sahra I, Jacquel A, Robert G, Cluzeau T, Deckert M, Tichet M, Chéli Y, Cassuto JP, Raynaud S, Legros L, Pasquet JM, Mahon FX, Luciano F, Auberger P. Puissant A, et al. Among authors: fenouille n. J Mol Cell Biol. 2012 Aug;4(4):207-20. doi: 10.1093/jmcb/mjs010. Epub 2012 Mar 31. J Mol Cell Biol. 2012. PMID: 22467682
When autophagy meets cancer through p62/SQSTM1.
Puissant A, Fenouille N, Auberger P. Puissant A, et al. Among authors: fenouille n. Am J Cancer Res. 2012;2(4):397-413. Epub 2012 Jun 28. Am J Cancer Res. 2012. PMID: 22860231 Free PMC article.
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.
Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A, Lacour JP, Ballotti R, Deckert M, Tartare-Deckert S. Fenouille N, et al. PLoS One. 2012;7(7):e40378. doi: 10.1371/journal.pone.0040378. Epub 2012 Jul 20. PLoS One. 2012. PMID: 22911700 Free PMC article.
26 results