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The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation.
Cnop M, Hughes SJ, Igoillo-Esteve M, Hoppa MB, Sayyed F, van de Laar L, Gunter JH, de Koning EJ, Walls GV, Gray DW, Johnson PR, Hansen BC, Morris JF, Pipeleers-Marichal M, Cnop I, Clark A. Cnop M, et al. Among authors: clark a. Diabetologia. 2010 Feb;53(2):321-30. doi: 10.1007/s00125-009-1562-x. Epub 2009 Oct 24. Diabetologia. 2010. PMID: 19855953
Multivesicular exocytosis in rat pancreatic beta cells.
Hoppa MB, Jones E, Karanauskaite J, Ramracheya R, Braun M, Collins SC, Zhang Q, Clark A, Eliasson L, Genoud C, Macdonald PE, Monteith AG, Barg S, Galvanovskis J, Rorsman P. Hoppa MB, et al. Among authors: clark a. Diabetologia. 2012 Apr;55(4):1001-12. doi: 10.1007/s00125-011-2400-5. Epub 2011 Dec 22. Diabetologia. 2012. PMID: 22189485 Free PMC article.
Longevity of human islet α- and β-cells.
Cnop M, Igoillo-Esteve M, Hughes SJ, Walker JN, Cnop I, Clark A. Cnop M, et al. Among authors: clark a. Diabetes Obes Metab. 2011 Oct;13 Suppl 1:39-46. doi: 10.1111/j.1463-1326.2011.01443.x. Diabetes Obes Metab. 2011. PMID: 21824255 Review.
A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker.
Flamez D, Roland I, Berton A, Kutlu B, Dufrane D, Beckers MC, De Waele E, Rooman I, Bouwens L, Clark A, Lonneux M, Jamar JF, Goldman S, Maréchal D, Goodman N, Gianello P, Van Huffel C, Salmon I, Eizirik DL. Flamez D, et al. Among authors: clark a. Diabetologia. 2010 Jul;53(7):1372-83. doi: 10.1007/s00125-010-1714-z. Epub 2010 Apr 9. Diabetologia. 2010. PMID: 20379810
8,025 results