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Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42.
J Bacteriol. 2011 Jan;193(1):215-24. doi: 10.1128/JB.00784-10. Epub 2010 Oct 22.
J Bacteriol. 2011.
PMID: 20971906
Free PMC article.
Engineering unnatural variants of plantazolicin through codon reprogramming.
Deane CD, Melby JO, Molohon KJ, Susarrey AR, Mitchell DA.
Deane CD, et al. Among authors: molohon kj.
ACS Chem Biol. 2013 Sep 20;8(9):1998-2008. doi: 10.1021/cb4003392. Epub 2013 Jul 3.
ACS Chem Biol. 2013.
PMID: 23823732
Free PMC article.
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Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics.
Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA.
Molohon KJ, et al.
ACS Chem Biol. 2011 Dec 16;6(12):1307-13. doi: 10.1021/cb200339d. Epub 2011 Oct 6.
ACS Chem Biol. 2011.
PMID: 21950656
Free PMC article.
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Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane.
Molohon KJ, Saint-Vincent PMB, Park S, Doroghazi JR, Maxson T, Hershfield JR, Flatt KM, Schroeder NE, Ha T, Mitchell DA.
Molohon KJ, et al.
ACS Infect Dis. 2016 Mar 10;2(3):207-220. doi: 10.1021/acsinfecdis.5b00115. Epub 2015 Dec 23.
ACS Infect Dis. 2016.
PMID: 27152321
Free PMC article.
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HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, Oldfield E.
Zhang Y, et al. Among authors: molohon kj.
ACS Med Chem Lett. 2012 Apr 3;3(5):402-406. doi: 10.1021/ml300038t.
ACS Med Chem Lett. 2012.
PMID: 22662288
Free PMC article.
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Antibacterial drug leads targeting isoprenoid biosynthesis.
Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, Nizet V, McCammon JA, Oldfield E.
Zhu W, et al. Among authors: molohon kj.
Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):123-8. doi: 10.1073/pnas.1219899110. Epub 2012 Dec 17.
Proc Natl Acad Sci U S A. 2013.
PMID: 23248302
Free PMC article.
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Multitarget drug discovery for tuberculosis and other infectious diseases.
Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, Molohon K, Orlean P, Mitchell DA, Freitas-Junior L, Ren F, Sun H, Jiang T, Li Y, Guo RT, Cole ST, Gennis RB, Crick DC, Oldfield E.
Li K, et al.
J Med Chem. 2014 Apr 10;57(7):3126-39. doi: 10.1021/jm500131s. Epub 2014 Apr 1.
J Med Chem. 2014.
PMID: 24568559
Free PMC article.
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