Swayze EE - Search Results

1

Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.

Gagnon KT, Pendergraff HM, Deleavey GF, Swayze EE, Potier P, Randolph J, Roesch EB, Chattopadhyaya J, Damha MJ, Bennett CF, Montaillier C, Lemaitre M, Corey DR. Gagnon KT, et al. Among authors: swayze ee. Biochemistry. 2010 Nov 30;49(47):10166-78. doi: 10.1021/bi101208k. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21028906 Free PMC article.

2

Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.

Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Maier MA, et al. Among authors: swayze ee. J Med Chem. 2006 Apr 20;49(8):2534-42. doi: 10.1021/jm051275y. J Med Chem. 2006. PMID: 16610796

3

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals.

Swayze EE, Siwkowski AM, Wancewicz EV, Migawa MT, Wyrzykiewicz TK, Hung G, Monia BP, Bennett CF. Swayze EE, et al. Nucleic Acids Res. 2007;35(2):687-700. doi: 10.1093/nar/gkl1071. Epub 2006 Dec 19. Nucleic Acids Res. 2007. PMID: 17182632 Free PMC article.

4

Potent inhibition of microRNA in vivo without degradation.

Davis S, Propp S, Freier SM, Jones LE, Serra MJ, Kinberger G, Bhat B, Swayze EE, Bennett CF, Esau C. Davis S, et al. Among authors: swayze ee. Nucleic Acids Res. 2009 Jan;37(1):70-7. doi: 10.1093/nar/gkn904. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015151 Free PMC article.

5

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.

Bennett CF, Swayze EE. Bennett CF, et al. Among authors: swayze ee. Annu Rev Pharmacol Toxicol. 2010;50:259-93. doi: 10.1146/annurev.pharmtox.010909.105654. Annu Rev Pharmacol Toxicol. 2010. PMID: 20055705 Review.

6

Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue.

Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, Kinberger GA. Wancewicz EV, et al. Among authors: swayze ee. J Med Chem. 2010 May 27;53(10):3919-26. doi: 10.1021/jm901489k. J Med Chem. 2010. PMID: 20420385 Free PMC article.

7

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.

Hu J, Gagnon KT, Liu J, Watts JK, Syeda-Nawaz J, Bennett CF, Swayze EE, Randolph J, Chattopadhyaya J, Corey DR. Hu J, et al. Among authors: swayze ee. Biol Chem. 2011 Apr;392(4):315-25. doi: 10.1515/BC.2011.045. Epub 2011 Feb 7. Biol Chem. 2011. PMID: 21294677 Free PMC article.

8

Insights from crystal structures into the opposite effects on RNA affinity caused by the S- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic acid.

Pallan PS, Yu J, Allerson CR, Swayze EE, Seth P, Egli M. Pallan PS, et al. Among authors: swayze ee. Biochemistry. 2012 Jan 10;51(1):7-9. doi: 10.1021/bi201810r. Epub 2011 Dec 29. Biochemistry. 2012. PMID: 22229409 Free PMC article.

9

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.

Yu D, Pendergraff H, Liu J, Kordasiewicz HB, Cleveland DW, Swayze EE, Lima WF, Crooke ST, Prakash TP, Corey DR. Yu D, et al. Among authors: swayze ee. Cell. 2012 Aug 31;150(5):895-908. doi: 10.1016/j.cell.2012.08.002. Cell. 2012. PMID: 22939619 Free PMC article.

10

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.

Liu J, Yu D, Aiba Y, Pendergraff H, Swayze EE, Lima WF, Hu J, Prakash TP, Corey DR. Liu J, et al. Among authors: swayze ee. Nucleic Acids Res. 2013 Nov;41(20):9570-83. doi: 10.1093/nar/gkt693. Epub 2013 Aug 9. Nucleic Acids Res. 2013. PMID: 23935115 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

149 results

Search Page