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Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.
Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD. Gupte R, et al. Among authors: siddam a. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7525-8. doi: 10.1016/j.bmcl.2010.09.115. Epub 2010 Oct 8. Bioorg Med Chem Lett. 2010. PMID: 21051230 Free PMC article.
Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.
Gupte R, Patil R, Liu J, Wang Y, Lee SC, Fujiwara Y, Fells J, Bolen AL, Emmons-Thompson K, Yates CR, Siddam A, Panupinthu N, Pham TC, Baker DL, Parrill AL, Mills GB, Tigyi G, Miller DD. Gupte R, et al. Among authors: siddam a. ChemMedChem. 2011 May 2;6(5):922-35. doi: 10.1002/cmdc.201000425. Epub 2011 Apr 4. ChemMedChem. 2011. PMID: 21465666 Free PMC article.
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development.
Aryal S, Viet J, Weatherbee BAT, Siddam AD, Hernandez FG, Gautier-Courteille C, Paillard L, Lachke SA. Aryal S, et al. Among authors: siddam ad. Hum Genet. 2020 Dec;139(12):1541-1554. doi: 10.1007/s00439-020-02195-7. Epub 2020 Jun 27. Hum Genet. 2020. PMID: 32594240 Free PMC article.
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology.
Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. Barnum CE, et al. Among authors: siddam ad. Hum Mol Genet. 2020 Jul 29;29(12):2076-2097. doi: 10.1093/hmg/ddaa096. Hum Mol Genet. 2020. PMID: 32420594 Free PMC article.
17 results