Crighton D - Search Results

1

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival.

Croft DR, Crighton D, Samuel MS, Lourenco FC, Munro J, Wood J, Bensaad K, Vousden KH, Sansom OJ, Ryan KM, Olson MF. Croft DR, et al. Among authors: crighton d. Cell Res. 2011 Apr;21(4):666-82. doi: 10.1038/cr.2010.154. Epub 2010 Nov 16. Cell Res. 2011. PMID: 21079653 Free PMC article.

2

Splicing DNA-damage responses to tumour cell death.

Crighton D, Ryan KM. Crighton D, et al. Biochim Biophys Acta. 2004 Dec 10;1705(1):3-15. doi: 10.1016/j.bbcan.2004.09.001. Biochim Biophys Acta. 2004. PMID: 15585169 Review.

3

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. Crighton D, et al. Cell. 2006 Jul 14;126(1):121-34. doi: 10.1016/j.cell.2006.05.034. Cell. 2006. PMID: 16839881 Free article.

4

DRAM links autophagy to p53 and programmed cell death.

Crighton D, Wilkinson S, Ryan KM. Crighton D, et al. Autophagy. 2007 Jan-Feb;3(1):72-4. doi: 10.4161/auto.3438. Epub 2007 Jan 28. Autophagy. 2007. PMID: 17102582 Review.

5

p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.

O'Prey J, Crighton D, Martin AG, Vousden KH, Fearnhead HO, Ryan KM. O'Prey J, et al. Among authors: crighton d. Cell Cycle. 2010 Mar 1;9(5):947-52. doi: 10.4161/cc.9.5.10872. Epub 2010 Mar 7. Cell Cycle. 2010. PMID: 20160496

6

p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death.

Baudot AD, Crighton D, O'Prey J, Somers J, Sierra Gonzalez P, Ryan KM. Baudot AD, et al. Among authors: crighton d. Cell Cycle. 2016 Sep;15(17):2299-308. doi: 10.1080/15384101.2016.1191714. Epub 2016 Jun 17. Cell Cycle. 2016. PMID: 27315169 Free PMC article.

7

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells.

Scott RW, Hooper S, Crighton D, Li A, König I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, Dawson J, Machesky L, Anderson KI, Sahai EA, Olson MF. Scott RW, et al. Among authors: crighton d. J Cell Biol. 2010 Oct 4;191(1):169-85. doi: 10.1083/jcb.201002041. Epub 2010 Sep 27. J Cell Biol. 2010. PMID: 20876278 Free PMC article.

8

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death.

Crighton D, O'Prey J, Bell HS, Ryan KM. Crighton D, et al. Cell Death Differ. 2007 Jun;14(6):1071-9. doi: 10.1038/sj.cdd.4402108. Epub 2007 Feb 16. Cell Death Differ. 2007. PMID: 17304243

9

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

Bell HS, Dufes C, O'Prey J, Crighton D, Bergamaschi D, Lu X, Schätzlein AG, Vousden KH, Ryan KM. Bell HS, et al. Among authors: crighton d. J Clin Invest. 2007 Apr;117(4):1008-18. doi: 10.1172/JCI28920. Epub 2007 Mar 8. J Clin Invest. 2007. PMID: 17347683 Free PMC article.

10

Trailblazing LIM kinases take the lead in collective tumor cell invasion.

Crighton D, Olson MF. Crighton D, et al. Bioarchitecture. 2011 Jan;1(1):5-8. doi: 10.4161/bioa.1.1.14628. Bioarchitecture. 2011. PMID: 21866254 Free PMC article.

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