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Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching.
Eichhoff OM, Weeraratna A, Zipser MC, Denat L, Widmer DS, Xu M, Kriegl L, Kirchner T, Larue L, Dummer R, Hoek KS. Eichhoff OM, et al. Among authors: zipser mc. Pigment Cell Melanoma Res. 2011 Aug;24(4):631-42. doi: 10.1111/j.1755-148X.2011.00871.x. Epub 2011 Jun 9. Pigment Cell Melanoma Res. 2011. PMID: 21599871
Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders.
Schad K, Baumann Conzett K, Zipser MC, Enderlin V, Kamarashev J, French LE, Dummer R. Schad K, et al. Among authors: zipser mc. Clin Cancer Res. 2010 Feb 1;16(3):1058-64. doi: 10.1158/1078-0432.CCR-09-1766. Epub 2010 Jan 26. Clin Cancer Res. 2010. PMID: 20103661 Clinical Trial.
MEK1 mutations confer resistance to MEK and B-RAF inhibition.
Emery CM, Vijayendran KG, Zipser MC, Sawyer AM, Niu L, Kim JJ, Hatton C, Chopra R, Oberholzer PA, Karpova MB, MacConaill LE, Zhang J, Gray NS, Sellers WR, Dummer R, Garraway LA. Emery CM, et al. Among authors: zipser mc. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20411-6. doi: 10.1073/pnas.0905833106. Epub 2009 Nov 13. Proc Natl Acad Sci U S A. 2009. PMID: 19915144 Free PMC article.
Changing pathology with changing drugs: skin cancer.
Karpova MB, Barysch MJ, Zipser MC, Schönewolf N, French LE, Dummer R. Karpova MB, et al. Among authors: zipser mc. Pathobiology. 2011;78(2):61-75. doi: 10.1159/000314576. Epub 2011 Jun 14. Pathobiology. 2011. PMID: 21677470 Free article. Review.
High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade.
Kiessling MK, Oberholzer PA, Mondal C, Karpova MB, Zipser MC, Lin WM, Girardi M, Macconaill LE, Kehoe SM, Hatton C, French LE, Garraway LA, Polier G, Süss D, Klemke CD, Krammer PH, Gülow K, Dummer R. Kiessling MK, et al. Among authors: zipser mc. Blood. 2011 Feb 24;117(8):2433-40. doi: 10.1182/blood-2010-09-305128. Epub 2011 Jan 5. Blood. 2011. PMID: 21209378 Free PMC article.
16 results