Shanahan CM - Search Results

1

Nesprins LINC the nucleus and cytoskeleton.

Mellad JA, Warren DT, Shanahan CM. Mellad JA, et al. Among authors: shanahan cm. Curr Opin Cell Biol. 2011 Feb;23(1):47-54. doi: 10.1016/j.ceb.2010.11.006. Epub 2010 Dec 20. Curr Opin Cell Biol. 2011. PMID: 21177090 Review.

2

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

Zhang Q, Skepper JN, Yang F, Davies JD, Hegyi L, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. J Cell Sci. 2001 Dec;114(Pt 24):4485-98. doi: 10.1242/jcs.114.24.4485. J Cell Sci. 2001. PMID: 11792814

3

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle.

Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. J Cell Sci. 2005 Feb 15;118(Pt 4):673-87. doi: 10.1242/jcs.01642. Epub 2005 Jan 25. J Cell Sci. 2005. PMID: 15671068

4

Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?

Warren DT, Zhang Q, Weissberg PL, Shanahan CM. Warren DT, et al. Among authors: shanahan cm. Expert Rev Mol Med. 2005 Jun 13;7(11):1-15. doi: 10.1017/S1462399405009294. Expert Rev Mol Med. 2005. PMID: 15953398 Review.

5

Coupling of the nucleus and cytoplasm: role of the LINC complex.

Crisp M, Liu Q, Roux K, Rattner JB, Shanahan C, Burke B, Stahl PD, Hodzic D. Crisp M, et al. J Cell Biol. 2006 Jan 2;172(1):41-53. doi: 10.1083/jcb.200509124. Epub 2005 Dec 27. J Cell Biol. 2006. PMID: 16380439 Free PMC article.

6

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, Weissberg PL, Roberts RG, Wehnert M, Shanahan CM. Zhang Q, et al. Among authors: shanahan cm. Hum Mol Genet. 2007 Dec 1;16(23):2816-33. doi: 10.1093/hmg/ddm238. Epub 2007 Aug 29. Hum Mol Genet. 2007. PMID: 17761684

7

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM. Warren DT, et al. Among authors: shanahan cm. J Biol Chem. 2010 Jan 8;285(2):1311-20. doi: 10.1074/jbc.M109.032557. Epub 2009 Oct 27. J Biol Chem. 2010. PMID: 19861416 Free PMC article.

8

Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging.

Ragnauth CD, Warren DT, Liu Y, McNair R, Tajsic T, Figg N, Shroff R, Skepper J, Shanahan CM. Ragnauth CD, et al. Among authors: shanahan cm. Circulation. 2010 May 25;121(20):2200-10. doi: 10.1161/CIRCULATIONAHA.109.902056. Epub 2010 May 10. Circulation. 2010. PMID: 20458013

9

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging.

Warren DT, Shanahan CM. Warren DT, et al. Among authors: shanahan cm. Biochem Soc Trans. 2011 Dec;39(6):1780-5. doi: 10.1042/BST20110703. Biochem Soc Trans. 2011. PMID: 22103525 Review.

10

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

Rajgor D, Mellad JA, Autore F, Zhang Q, Shanahan CM. Rajgor D, et al. Among authors: shanahan cm. PLoS One. 2012;7(7):e40098. doi: 10.1371/journal.pone.0040098. Epub 2012 Jul 2. PLoS One. 2012. PMID: 22768332 Free PMC article.

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