Vite GD - Search Results

1

Novel pyrrolo[2,1-f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases.

Fink BE, Norris D, Mastalerz H, Chen P, Goyal B, Zhao Y, Kim SH, Vite GD, Lee FY, Zhang H, Oppenheimer S, Tokarski JS, Wong TW, Gavai AV. Fink BE, et al. Among authors: vite gd. Bioorg Med Chem Lett. 2011 Jan 15;21(2):781-5. doi: 10.1016/j.bmcl.2010.11.100. Epub 2010 Nov 30. Bioorg Med Chem Lett. 2011. PMID: 21177105

2

Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.

Leftheris K, Kline T, Vite GD, Cho YH, Bhide RS, Patel DV, Patel MM, Schmidt RJ, Weller HN, Andahazy ML, Carboni JM, Gullo-Brown JL, Lee FY, Ricca C, Rose WC, Yan N, Barbacid M, Hunt JT, Meyers CA, Seizinger BR, Zahler R, Manne V. Leftheris K, et al. Among authors: vite gd. J Med Chem. 1996 Jan 5;39(1):224-36. doi: 10.1021/jm950642a. J Med Chem. 1996. PMID: 8568812

3

BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.

Lee FY, Borzilleri R, Fairchild CR, Kim SH, Long BH, Reventos-Suarez C, Vite GD, Rose WC, Kramer RA. Lee FY, et al. Among authors: vite gd. Clin Cancer Res. 2001 May;7(5):1429-37. Clin Cancer Res. 2001. PMID: 11350914

4

Synthesis and biological activity of novel epothilone aziridines.

Regueiro-Ren A, Borzilleri RM, Zheng X, Kim SH, Johnson JA, Fairchild CR, Lee FY, Long BH, Vite GD. Regueiro-Ren A, et al. Among authors: vite gd. Org Lett. 2001 Aug 23;3(17):2693-6. doi: 10.1021/ol016273w. Org Lett. 2001. PMID: 11506611

5

SAR and pH stability of cyano-substituted epothilones.

Regueiro-Ren A, Leavitt K, Kim SH, Höfle G, Kiffe M, Gougoutas JZ, DiMarco JD, Lee FY, Fairchild CR, Long BH, Vite GD. Regueiro-Ren A, et al. Among authors: vite gd. Org Lett. 2002 Oct 31;4(22):3815-8. doi: 10.1021/ol026589j. Org Lett. 2002. PMID: 12599466

6

Apoptotic and cytostatic farnesyltransferase inhibitors have distinct pharmacology and efficacy profiles in tumor models.

Manne V, Lee FY, Bol DK, Gullo-Brown J, Fairchild CR, Lombardo LJ, Smykla RA, Vite GD, Wen ML, Yu C, Wong TW, Hunt JT. Manne V, et al. Among authors: vite gd. Cancer Res. 2004 Jun 1;64(11):3974-80. doi: 10.1158/0008-5472.CAN-03-3849. Cancer Res. 2004. PMID: 15173010

7

Identification of novel functional inhibitors of 17beta-hydroxysteroid dehydrogenase type III (17beta-HSD3).

Spires TE, Fink BE, Kick EK, You D, Rizzo CA, Takenaka I, Lawrence RM, Ruan Z, Salvati ME, Vite GD, Weinmann R, Attar RM, Gottardis MM, Lorenzi MV. Spires TE, et al. Among authors: vite gd. Prostate. 2005 Oct 1;65(2):159-70. doi: 10.1002/pros.20279. Prostate. 2005. PMID: 15924334

8

New dual inhibitors of EGFR and HER2 protein tyrosine kinases.

Fink BE, Vite GD, Mastalerz H, Kadow JF, Kim SH, Leavitt KJ, Du K, Crews D, Mitt T, Wong TW, Hunt JT, Vyas DM, Tokarski JS. Fink BE, et al. Among authors: vite gd. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4774-9. doi: 10.1016/j.bmcl.2005.07.027. Bioorg Med Chem Lett. 2005. PMID: 16111887

9

Identification of a novel series of tetrahydrodibenzazocines as inhibitors of 17beta-hydroxysteroid dehydrogenase type 3.

Fink BE, Gavai AV, Tokarski JS, Goyal B, Misra R, Xiao HY, Kimball SD, Han WC, Norris D, Spires TE, You D, Gottardis MM, Lorenzi MV, Vite GD. Fink BE, et al. Among authors: vite gd. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1532-6. doi: 10.1016/j.bmcl.2005.12.039. Epub 2006 Jan 4. Bioorg Med Chem Lett. 2006. PMID: 16386902

10

Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics.

Kellar KA, Lorenzi MV, Ho CP, You D, Wen ML, Ryseck RP, Oppenheimer S, Fink BE, Vite GD, Rowley BR, Yu C, Bol DK, Lee FY, Wong TW. Kellar KA, et al. Among authors: vite gd. Mol Cancer Ther. 2006 Jun;5(6):1571-6. doi: 10.1158/1535-7163.MCT-06-0078. Mol Cancer Ther. 2006. PMID: 16818516

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