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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.
Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. Kapoor A, et al. Among authors: leroy g. Nature. 2010 Dec 23;468(7327):1105-9. doi: 10.1038/nature09590. Nature. 2010. PMID: 21179167 Free PMC article.
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency.
Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. Gaspar-Maia A, et al. Among authors: leroy g. Nat Commun. 2013;4:1565. doi: 10.1038/ncomms2582. Nat Commun. 2013. PMID: 23463008 Free PMC article.
H3R42me2a is a histone modification with positive transcriptional effects.
Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. Casadio F, et al. Among authors: leroy g. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14894-9. doi: 10.1073/pnas.1312925110. Epub 2013 Aug 26. Proc Natl Acad Sci U S A. 2013. PMID: 23980157 Free PMC article.
Asymmetrically modified nucleosomes.
Voigt P, LeRoy G, Drury WJ 3rd, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Voigt P, et al. Among authors: leroy g. Cell. 2012 Sep 28;151(1):181-93. doi: 10.1016/j.cell.2012.09.002. Cell. 2012. PMID: 23021224 Free PMC article.
367 results