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mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging.
Van Skike CE, Lin AL, Roberts Burbank R, Halloran JJ, Hernandez SF, Cuvillier J, Soto VY, Hussong SA, Jahrling JB, Javors MA, Hart MJ, Fischer KE, Austad SN, Galvan V. Van Skike CE, et al. Among authors: fischer ke. Aging Cell. 2020 Jan;19(1):e13057. doi: 10.1111/acel.13057. Epub 2019 Nov 6. Aging Cell. 2020. PMID: 31693798 Free PMC article.
Sex Differences in Aging: Genomic Instability.
Fischer KE, Riddle NC. Fischer KE, et al. J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):166-174. doi: 10.1093/gerona/glx105. J Gerontol A Biol Sci Med Sci. 2018. PMID: 28575157 Free PMC article. Review.
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.
Zhang N, Valentine JM, Zhou Y, Li ME, Zhang Y, Bhattacharya A, Walsh ME, Fischer KE, Austad SN, Osmulski P, Gaczynska M, Shoelson SE, Van Remmen H, Chen HI, Chen Y, Liang H, Musi N. Zhang N, et al. Among authors: fischer ke. Aging Cell. 2017 Aug;16(4):847-858. doi: 10.1111/acel.12613. Epub 2017 May 29. Aging Cell. 2017. PMID: 28556540 Free PMC article.
Sco2 deficient mice develop increased adiposity and insulin resistance.
Hill S, Deepa SS, Sataranatarajan K, Premkumar P, Pulliam D, Liu Y, Soto VY, Fischer KE, Van Remmen H. Hill S, et al. Among authors: fischer ke. Mol Cell Endocrinol. 2017 Nov 5;455:103-114. doi: 10.1016/j.mce.2017.03.019. Epub 2017 Apr 18. Mol Cell Endocrinol. 2017. PMID: 28428045 Free PMC article.
46 results