Downward J - Search Results

1

Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells.

Vento MT, Zazzu V, Loffreda A, Cross JR, Downward J, Stoppelli MP, Iaccarino I. Vento MT, et al. Among authors: downward j. PLoS One. 2010 Dec 20;5(12):e15636. doi: 10.1371/journal.pone.0015636. PLoS One. 2010. PMID: 21203533 Free PMC article.

2

Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor.

Alfano D, Votta G, Schulze A, Downward J, Caputi M, Stoppelli MP, Iaccarino I. Alfano D, et al. Among authors: downward j. Mol Cell Biol. 2010 Apr;30(7):1838-51. doi: 10.1128/MCB.01442-09. Epub 2010 Feb 1. Mol Cell Biol. 2010. PMID: 20123981 Free PMC article.

3

c-Myc induces cytochrome c release in Rat1 fibroblasts by increasing outer mitochondrial membrane permeability in a Bid-dependent manner.

Iaccarino I, Hancock D, Evan G, Downward J. Iaccarino I, et al. Among authors: downward j. Cell Death Differ. 2003 May;10(5):599-608. doi: 10.1038/sj.cdd.4401211. Cell Death Differ. 2003. PMID: 12728258

4

Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur.

Cross JR, Postigo A, Blight K, Downward J. Cross JR, et al. Among authors: downward j. Cell Death Differ. 2008 Jun;15(6):997-1008. doi: 10.1038/cdd.2008.14. Epub 2008 Feb 15. Cell Death Differ. 2008. PMID: 18274554

5

Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis.

Postigo A, Cross JR, Downward J, Way M. Postigo A, et al. Among authors: downward j. Cell Death Differ. 2006 Oct;13(10):1651-62. doi: 10.1038/sj.cdd.4401853. Epub 2006 Jan 27. Cell Death Differ. 2006. PMID: 16439990

6

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif.

Martins LM, Iaccarino I, Tenev T, Gschmeissner S, Totty NF, Lemoine NR, Savopoulos J, Gray CW, Creasy CL, Dingwall C, Downward J. Martins LM, et al. Among authors: downward j. J Biol Chem. 2002 Jan 4;277(1):439-44. doi: 10.1074/jbc.M109784200. Epub 2001 Oct 15. J Biol Chem. 2002. PMID: 11602612 Free article.

7

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.

Pardo OE, Arcaro A, Salerno G, Raguz S, Downward J, Seckl MJ. Pardo OE, et al. Among authors: downward j. J Biol Chem. 2002 Apr 5;277(14):12040-6. doi: 10.1074/jbc.M109006200. Epub 2002 Jan 28. J Biol Chem. 2002. Retraction in: J Biol Chem. 2015 Jun 19;290(25):15390. doi: 10.1074/jbc.A115.109006. PMID: 11815602 Free article. Retracted.

8

PI 3-kinase, Akt and cell survival.

Downward J. Downward J. Semin Cell Dev Biol. 2004 Apr;15(2):177-82. doi: 10.1016/j.semcdb.2004.01.002. Semin Cell Dev Biol. 2004. PMID: 15209377 Review.

9

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis.

Marani M, Tenev T, Hancock D, Downward J, Lemoine NR. Marani M, et al. Among authors: downward j. Mol Cell Biol. 2002 Jun;22(11):3577-89. doi: 10.1128/MCB.22.11.3577-3589.2002. Mol Cell Biol. 2002. PMID: 11997495 Free PMC article.

10

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression.

Delpuech O, Griffiths B, East P, Essafi A, Lam EW, Burgering B, Downward J, Schulze A. Delpuech O, et al. Among authors: downward j. Mol Cell Biol. 2007 Jul;27(13):4917-30. doi: 10.1128/MCB.01789-06. Epub 2007 Apr 23. Mol Cell Biol. 2007. PMID: 17452451 Free PMC article.

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