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Chemical generation of bispecific antibodies.
Doppalapudi VR, Huang J, Liu D, Jin P, Liu B, Li L, Desharnais J, Hagen C, Levin NJ, Shields MJ, Parish M, Murphy RE, Del Rosario J, Oates BD, Lai JY, Matin MJ, Ainekulu Z, Bhat A, Bradshaw CW, Woodnutt G, Lerner RA, Lappe RW. Doppalapudi VR, et al. Among authors: li l. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22611-6. doi: 10.1073/pnas.1016478108. Epub 2010 Dec 13. Proc Natl Acad Sci U S A. 2010. PMID: 21149738 Free PMC article.
Antitumor efficacy of a thrombospondin 1 mimetic CovX-body.
Li L, Leedom TA, Do J, Huang H, Lai J, Johnson K, Osothprarop TF, Rizzo JD, Doppalapudi VR, Bradshaw CW, Lappe RW, Woodnutt G, Levin NJ, Pirie-Shepherd SR. Li L, et al. Transl Oncol. 2011 Aug;4(4):249-57. doi: 10.1593/tlo.11136. Epub 2011 Aug 1. Transl Oncol. 2011. PMID: 21804921 Free PMC article.
Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody.
Huang J, Ishino T, Chen G, Rolzin P, Osothprarop TF, Retting K, Li L, Jin P, Matin MJ, Huyghe B, Talukdar S, Bradshaw CW, Palanki M, Violand BN, Woodnutt G, Lappe RW, Ogilvie K, Levin N. Huang J, et al. Among authors: li l. J Pharmacol Exp Ther. 2013 Aug;346(2):270-80. doi: 10.1124/jpet.113.204420. Epub 2013 May 29. J Pharmacol Exp Ther. 2013. PMID: 23720456
Chemically programmed antibodies: endothelin receptor targeting CovX-Bodies.
Doppalapudi VR, Tryder N, Li L, Aja T, Griffith D, Liao FF, Roxas G, Ramprasad MP, Bradshaw C, Barbas CF 3rd. Doppalapudi VR, et al. Among authors: li l. Bioorg Med Chem Lett. 2007 Jan 15;17(2):501-6. doi: 10.1016/j.bmcl.2006.10.009. Epub 2006 Oct 7. Bioorg Med Chem Lett. 2007. PMID: 17055724
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