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CKIα ablation highlights a critical role for p53 in invasiveness control.
Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y. Elyada E, et al. Among authors: alitalo k. Nature. 2011 Feb 17;470(7334):409-13. doi: 10.1038/nature09673. Nature. 2011. PMID: 21331045
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y. Pribluda A, et al. Among authors: alitalo k. Cancer Cell. 2013 Aug 12;24(2):242-56. doi: 10.1016/j.ccr.2013.06.005. Epub 2013 Jul 25. Cancer Cell. 2013. PMID: 23890787 Free article.
Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K. Wiener Z, et al. Among authors: alitalo k. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36. doi: 10.1073/pnas.1406444111. Epub 2014 May 13. Proc Natl Acad Sci U S A. 2014. PMID: 24825889 Free PMC article.
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.
Tammela T, Zarkada G, Wallgard E, Murtomäki A, Suchting S, Wirzenius M, Waltari M, Hellström M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Ylä-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K. Tammela T, et al. Among authors: alitalo k. Nature. 2008 Jul 31;454(7204):656-60. doi: 10.1038/nature07083. Epub 2008 Jun 25. Nature. 2008. PMID: 18594512
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.
Holopainen T, López-Alpuche V, Zheng W, Heljasvaara R, Jones D, He Y, Tvorogov D, D'Amico G, Wiener Z, Andersson LC, Pihlajaniemi T, Min W, Alitalo K. Holopainen T, et al. Among authors: alitalo k. Cancer Res. 2012 Jul 15;72(14):3512-21. doi: 10.1158/0008-5472.CAN-11-1070. Epub 2012 May 16. Cancer Res. 2012. PMID: 22593188
721 results