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Phenotypic assays and sequencing are less sensitive than point mutation assays for detection of resistance in mixed HIV-1 genotypic populations.
Van Laethem K, Van Vaerenbergh K, Schmit JC, Sprecher S, Hermans P, De Vroey V, Schuurman R, Harrer T, Witvrouw M, Van Wijngaerden E, Stuyver L, Van Ranst M, Desmyter J, De Clercq E, Vandamme AM. Van Laethem K, et al. Among authors: de vroey v, de clercq e. J Acquir Immune Defic Syndr. 1999 Oct 1;22(2):107-18. doi: 10.1097/00126334-199910010-00001. J Acquir Immune Defic Syndr. 1999. PMID: 10843523
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
Van Vaerenbergh K, Van Laethem K, Van Wijngaerden E, Schmit JC, Schneider F, Ruiz L, Clotet B, Verhofstede C, Van Wanzeele F, Muyldermans G, Simons P, Stuyver L, Hermans P, Evans C, De Clercq E, Desmyter J, Vandamme AM. Van Vaerenbergh K, et al. Among authors: de clercq e. AIDS Res Hum Retroviruses. 2000 Apr 10;16(6):529-37. doi: 10.1089/088922200308945. AIDS Res Hum Retroviruses. 2000. PMID: 10777143
Anti-HIV-1 activity of benzothiadiazine dioxide.
Martinez A, Gil C, Castro A, Perez C, Witvrouw M, Pannecouque C, Balzarini J, De Clercq E. Martinez A, et al. Among authors: de clercq e. Antivir Chem Chemother. 2001 Nov;12(6):347-51. doi: 10.1177/095632020101200604. Antivir Chem Chemother. 2001. PMID: 12018679 Free article.
Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain.
Schmit JC, Cogniaux J, Hermans P, Van Vaeck C, Sprecher S, Van Remoortel B, Witvrouw M, Balzarini J, Desmyter J, De Clercq E, Vandamme AM. Schmit JC, et al. Among authors: de clercq e. J Infect Dis. 1996 Nov;174(5):962-8. doi: 10.1093/infdis/174.5.962. J Infect Dis. 1996. PMID: 8896496
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.
Witvrouw M, Balzarini J, Pannecouque C, Jhaumeer-Laulloo S, Esté JA, Schols D, Cherepanov P, Schmit JC, Debyser Z, Vandamme AM, Desmyter J, Ramadas SR, de Clercq E. Witvrouw M, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1997 Feb;41(2):262-8. doi: 10.1128/AAC.41.2.262. Antimicrob Agents Chemother. 1997. PMID: 9021177 Free PMC article.
2,277 results