Mitogen-activated protein kinases regulate palytoxin-induced calcium influx and cytotoxicity in cultured neurons.
Vale C, Gómez-Limia B, Vieytes MR, Botana LM.
Vale C, et al.
Br J Pharmacol. 2007 Sep;152(2):256-66. doi: 10.1038/sj.bjp.0707389. Epub 2007 Jul 16.
Br J Pharmacol. 2007.
PMID: 17641674
Free PMC article.
Palytoxin is highly neurotoxic and increases the cytosolic calcium concentration ([Ca(2+)](c)) while decreasing intracellular pH (pH(i)) in neurons (Vale et al., 2006; Vale-Gonzalez et al., 2007). ...EXPERIMENTAL APPROACH: The role of different protein kinase …
Palytoxin is highly neurotoxic and increases the cytosolic calcium concentration ([Ca(2+)](c)) while decreasing intracellular pH (pH( …