Flanagan L - Search Results

1

Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization.

Flanagan L, Sebastia J, Delgado ME, Lennon JC, Rehm M. Flanagan L, et al. Biochim Biophys Acta. 2011 May;1813(5):819-26. doi: 10.1016/j.bbamcr.2011.02.011. Epub 2011 Feb 24. Biochim Biophys Acta. 2011. PMID: 21354220 Free article.

2

XIAP impairs Smac release from the mitochondria during apoptosis.

Flanagan L, Sebastià J, Tuffy LP, Spring A, Lichawska A, Devocelle M, Prehn JH, Rehm M. Flanagan L, et al. Cell Death Dis. 2010 Jun 3;1(6):e49. doi: 10.1038/cddis.2010.26. Cell Death Dis. 2010. PMID: 21364655 Free PMC article.

3

Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.

Schmid J, Dussmann H, Boukes GJ, Flanagan L, Lindner AU, O'Connor CL, Rehm M, Prehn JH, Huber HJ. Schmid J, et al. Among authors: flanagan l. J Biol Chem. 2012 Nov 30;287(49):41546-59. doi: 10.1074/jbc.M112.411827. Epub 2012 Oct 4. J Biol Chem. 2012. PMID: 23038270 Free PMC article.

4

Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death.

Ludwig-Galezowska AH, Flanagan L, Rehm M. Ludwig-Galezowska AH, et al. Among authors: flanagan l. J Cell Mol Med. 2011 May;15(5):1044-53. doi: 10.1111/j.1582-4934.2010.01221.x. J Cell Mol Med. 2011. PMID: 21129150 Free PMC article. Review.

5

Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.

Zakaria Z, Tivnan A, Flanagan L, Murray DW, Salvucci M, Stringer BW, Day BW, Boyd AW, Kögel D, Rehm M, O'Brien DF, Byrne AT, Prehn JH. Zakaria Z, et al. Among authors: flanagan l. Br J Cancer. 2016 Jan 19;114(2):188-98. doi: 10.1038/bjc.2015.420. Epub 2015 Dec 10. Br J Cancer. 2016. PMID: 26657652 Free PMC article.

6

Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling.

Laussmann MA, Passante E, Hellwig CT, Tomiczek B, Flanagan L, Prehn JH, Huber HJ, Rehm M. Laussmann MA, et al. Among authors: flanagan l. J Biol Chem. 2012 Apr 27;287(18):14402-11. doi: 10.1074/jbc.M111.304378. Epub 2012 Mar 9. J Biol Chem. 2012. PMID: 22408249 Free PMC article.

7

A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer.

Salvucci M, Würstle ML, Morgan C, Curry S, Cremona M, Lindner AU, Bacon O, Resler AJ, Murphy ÁC, O'Byrne R, Flanagan L, Dasgupta S, Rice N, Pilati C, Zink E, Schöller LM, Toomey S, Lawler M, Johnston PG, Wilson R, Camilleri-Broët S, Salto-Tellez M, McNamara DA, Kay EW, Laurent-Puig P, Van Schaeybroeck S, Hennessy BT, Longley DB, Rehm M, Prehn JH. Salvucci M, et al. Among authors: flanagan l. Clin Cancer Res. 2017 Mar 1;23(5):1200-1212. doi: 10.1158/1078-0432.CCR-16-1084. Epub 2016 Sep 20. Clin Cancer Res. 2017. PMID: 27649552

8

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.

Flanagan L, Kehoe J, Fay J, Bacon O, Lindner AU, Kay EW, Deasy J, McNamara DA, Prehn JH. Flanagan L, et al. Radiat Oncol. 2015 Jun 13;10:131. doi: 10.1186/s13014-015-0437-1. Radiat Oncol. 2015. PMID: 26071313 Free PMC article.

9

Paracrine control of tissue regeneration and cell proliferation by Caspase-3.

Boland K, Flanagan L, Prehn JH. Boland K, et al. Among authors: flanagan l. Cell Death Dis. 2013 Jul 11;4(7):e725. doi: 10.1038/cddis.2013.250. Cell Death Dis. 2013. PMID: 23846227 Free PMC article. Review.

10

BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer.

Flanagan L, Lindner AU, de Chaumont C, Kehoe J, Fay J, Bacon O, Toomey S, Huber HJ, Hennessy BT, Kay EW, McNamara DA, Prehn JH. Flanagan L, et al. J Mol Med (Berl). 2015 Mar;93(3):315-26. doi: 10.1007/s00109-014-1221-7. Epub 2014 Nov 13. J Mol Med (Berl). 2015. PMID: 25388617

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