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MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
Kolbeck R, Kozhich A, Koike M, Peng L, Andersson CK, Damschroder MM, Reed JL, Woods R, Dall'acqua WW, Stephens GL, Erjefalt JS, Bjermer L, Humbles AA, Gossage D, Wu H, Kiener PA, Spitalny GL, Mackay CR, Molfino NA, Coyle AJ. Kolbeck R, et al. J Allergy Clin Immunol. 2010 Jun;125(6):1344-1353.e2. doi: 10.1016/j.jaci.2010.04.004. J Allergy Clin Immunol. 2010. PMID: 20513525
IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways.
Kearley J, Erjefalt JS, Andersson C, Benjamin E, Jones CP, Robichaud A, Pegorier S, Brewah Y, Burwell TJ, Bjermer L, Kiener PA, Kolbeck R, Lloyd CM, Coyle AJ, Humbles AA. Kearley J, et al. Among authors: kolbeck r. Am J Respir Crit Care Med. 2011 Apr 1;183(7):865-75. doi: 10.1164/rccm.200909-1462OC. Epub 2010 Oct 22. Am J Respir Crit Care Med. 2011. PMID: 20971830 Free PMC article.
Complement C5a potentiates uric acid crystal-induced IL-1β production.
An LL, Mehta P, Xu L, Turman S, Reimer T, Naiman B, Connor J, Sanjuan M, Kolbeck R, Fung M. An LL, et al. Among authors: kolbeck r. Eur J Immunol. 2014 Dec;44(12):3669-79. doi: 10.1002/eji.201444560. Epub 2014 Oct 28. Eur J Immunol. 2014. PMID: 25229885 Free article. Clinical Trial.
Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood.
Al-Garawi A, Fattouh R, Botelho F, Walker TD, Goncharova S, Moore CL, Mori M, Erjefalt JS, Chu DK, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M. Al-Garawi A, et al. Among authors: kolbeck r. Mucosal Immunol. 2011 Nov;4(6):682-94. doi: 10.1038/mi.2011.35. Epub 2011 Aug 31. Mucosal Immunol. 2011. PMID: 21881572 Free article.
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Chu DK, Mohammed-Ali Z, Jiménez-Saiz R, Walker TD, Goncharova S, Llop-Guevara A, Kong J, Gordon ME, Barra NG, Gillgrass AE, Van Seggelen H, Khan WI, Ashkar AA, Bramson JL, Humbles AA, Kolbeck R, Waserman S, Jordana M. Chu DK, et al. Among authors: kolbeck r. Mucosal Immunol. 2014 Nov;7(6):1395-404. doi: 10.1038/mi.2014.29. Epub 2014 Apr 30. Mucosal Immunol. 2014. PMID: 24781052 Free article.
143 results