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A role for dormant origins in tumor suppression.
Mol Cell. 2011 Mar 4;41(5):495-6. doi: 10.1016/j.molcel.2011.02.014.
Mol Cell. 2011.
PMID: 21362544
Free PMC article.
Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation.
Klotz-Noack K, McIntosh D, Schurch N, Pratt N, Blow JJ.
Klotz-Noack K, et al.
J Cell Sci. 2012 May 15;125(Pt 10):2436-45. doi: 10.1242/jcs.100883. Epub 2012 Feb 24.
J Cell Sci. 2012.
PMID: 22366459
Free PMC article.
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SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells.
Klotz-Noack K, Klinger B, Rivera M, Bublitz N, Uhlitz F, Riemer P, Lüthen M, Sell T, Kasack K, Gastl B, Ispasanie SSS, Simon T, Janssen N, Schwab M, Zuber J, Horst D, Blüthgen N, Schäfer R, Morkel M, Sers C.
Klotz-Noack K, et al.
Cell Rep. 2020 Sep 22;32(12):108184. doi: 10.1016/j.celrep.2020.108184.
Cell Rep. 2020.
PMID: 32966782
Free article.
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Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.
Gastl B, Klotz-Noack K, Klinger B, Ispasanie S, Salib KHF, Zuber J, Mamlouk S, Bublitz N, Blüthgen N, Horst D, Morkel M, Schäfer R, Sers C.
Gastl B, et al. Among authors: klotz noack k.
Cell Death Dis. 2020 Jul 1;11(7):499. doi: 10.1038/s41419-020-2704-9.
Cell Death Dis. 2020.
PMID: 32612138
Free PMC article.
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Mutation-specific effects of NRAS oncogenes in colorectal cancer cells.
Kuhn N, Klinger B, Uhlitz F, Sieber A, Rivera M, Klotz-Noack K, Fichtner I, Hoffmann J, Blüthgen N, Falk C, Sers C, Schäfer R.
Kuhn N, et al. Among authors: klotz noack k.
Adv Biol Regul. 2021 Jan;79:100778. doi: 10.1016/j.jbior.2020.100778. Epub 2020 Dec 31.
Adv Biol Regul. 2021.
PMID: 33431353
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Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz F, Bischoff P, Peidli S, Sieber A, Trinks A, Lüthen M, Obermayer B, Blanc E, Ruchiy Y, Sell T, Mamlouk S, Arsie R, Wei TT, Klotz-Noack K, Schwarz RF, Sawitzki B, Kamphues C, Beule D, Landthaler M, Sers C, Horst D, Blüthgen N, Morkel M.
Uhlitz F, et al. Among authors: klotz noack k.
EMBO Mol Med. 2021 Oct 7;13(10):e14123. doi: 10.15252/emmm.202114123. Epub 2021 Aug 19.
EMBO Mol Med. 2021.
PMID: 34409732
Free PMC article.
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.
Ozkan-Dagliyan I, Diehl JN, George SD, Schaefer A, Papke B, Klotz-Noack K, Waters AM, Goodwin CM, Gautam P, Pierobon M, Peng S, Gilbert TSK, Lin KH, Dagliyan O, Wennerberg K, Petricoin EF 3rd, Tran NL, Bhagwat SV, Tiu RV, Peng SB, Herring LE, Graves LM, Sers C, Wood KC, Cox AD, Der CJ.
Ozkan-Dagliyan I, et al. Among authors: klotz noack k.
Cell Rep. 2020 Jun 16;31(11):107764. doi: 10.1016/j.celrep.2020.107764.
Cell Rep. 2020.
PMID: 32553168
Free PMC article.
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PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.
Tan Y, Sun D, Jiang W, Klotz-Noack K, Vashisht AA, Wohlschlegel J, Widschwendter M, Spruck C.
Tan Y, et al. Among authors: klotz noack k.
Cancer Res. 2014 Apr 1;74(7):2006-14. doi: 10.1158/0008-5472.CAN-13-1263. Epub 2014 Feb 7.
Cancer Res. 2014.
PMID: 24509904
Free PMC article.
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