Leach CA - Search Results

1

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling.

Lui TT, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, Daulat AM, Angers S. Lui TT, et al. Among authors: leach ca. Mol Cell Biol. 2011 May;31(10):2053-65. doi: 10.1128/MCB.01094-10. Epub 2011 Mar 7. Mol Cell Biol. 2011. PMID: 21383061 Free PMC article.

2

Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format.

Tian X, Isamiddinova NS, Peroutka RJ, Goldenberg SJ, Mattern MR, Nicholson B, Leach C. Tian X, et al. Assay Drug Dev Technol. 2011 Apr;9(2):165-73. doi: 10.1089/adt.2010.0317. Epub 2010 Dec 6. Assay Drug Dev Technol. 2011. PMID: 21133675 Free PMC article.

3

Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.

Altun M, Kramer HB, Willems LI, McDermott JL, Leach CA, Goldenberg SJ, Kumar KG, Konietzny R, Fischer R, Kogan E, Mackeen MM, McGouran J, Khoronenkova SV, Parsons JL, Dianov GL, Nicholson B, Kessler BM. Altun M, et al. Among authors: leach ca. Chem Biol. 2011 Nov 23;18(11):1401-12. doi: 10.1016/j.chembiol.2011.08.018. Chem Biol. 2011. PMID: 22118674

4

Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities.

Nicholson B, Leach CA, Goldenberg SJ, Francis DM, Kodrasov MP, Tian X, Shanks J, Sterner DE, Bernal A, Mattern MR, Wilkinson KD, Butt TR. Nicholson B, et al. Among authors: leach ca. Protein Sci. 2008 Jun;17(6):1035-43. doi: 10.1110/ps.083450408. Epub 2008 Apr 18. Protein Sci. 2008. PMID: 18424514 Free PMC article.

5

A baker's dozen of ubiquitin.

Haas AL, Leach CA. Haas AL, et al. Among authors: leach ca. Cell Biochem Biophys. 2011 Jun;60(1-2):1. doi: 10.1007/s12013-011-9204-6. Cell Biochem Biophys. 2011. PMID: 21544573 No abstract available.

6

Detection and characterization of SUMO protease activity using a sensitive enzyme-based reporter assay.

Leach CA, Tian X, Mattern MR, Nicholson B. Leach CA, et al. Methods Mol Biol. 2009;497:269-81. doi: 10.1007/978-1-59745-566-4_18. Methods Mol Biol. 2009. PMID: 19107424 Review.

7

Novel approach for characterizing ubiquitin E3 ligase function.

Marblestone JG, Suresh Kumar KG, Eddins MJ, Leach CA, Sterner DE, Mattern MR, Nicholson B. Marblestone JG, et al. Among authors: leach ca. J Biomol Screen. 2010 Dec;15(10):1220-8. doi: 10.1177/1087057110380456. Epub 2010 Sep 23. J Biomol Screen. 2010. PMID: 20864734

8

Targeting the ubiquitin E3 ligase MuRF1 to inhibit muscle atrophy.

Eddins MJ, Marblestone JG, Suresh Kumar KG, Leach CA, Sterner DE, Mattern MR, Nicholson B. Eddins MJ, et al. Among authors: leach ca. Cell Biochem Biophys. 2011 Jun;60(1-2):113-8. doi: 10.1007/s12013-011-9175-7. Cell Biochem Biophys. 2011. PMID: 21448668

9

Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins.

Marblestone JG, Larocque JP, Mattern MR, Leach CA. Marblestone JG, et al. Among authors: leach ca. Biochim Biophys Acta. 2012 Nov;1823(11):2094-7. doi: 10.1016/j.bbamcr.2012.06.013. Epub 2012 Jun 18. Biochim Biophys Acta. 2012. PMID: 22721718 Free PMC article.

10

Deubiquitylase, deSUMOylase, and deISGylase activity microarrays for assay of substrate preference and functional modifiers.

Loch CM, Cuccherini CL, Leach CA, Strickler JE. Loch CM, et al. Among authors: leach ca. Mol Cell Proteomics. 2011 Jan;10(1):M110.002402. doi: 10.1074/mcp.M110.002402. Epub 2010 Oct 18. Mol Cell Proteomics. 2011. PMID: 20956615 Free PMC article.

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