Acosta-Alvear D - Search Results

1

A CHOP-regulated microRNA controls rhodopsin expression.

Behrman S, Acosta-Alvear D, Walter P. Behrman S, et al. J Cell Biol. 2011 Mar 21;192(6):919-27. doi: 10.1083/jcb.201010055. Epub 2011 Mar 14. J Cell Biol. 2011. PMID: 21402790 Free PMC article.

2

Pharmacological brake-release of mRNA translation enhances cognitive memory.

Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Sidrauski C, et al. Elife. 2013 May 28;2:e00498. doi: 10.7554/eLife.00498. Elife. 2013. PMID: 23741617 Free PMC article.

3

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.

Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. Lu M, et al. Science. 2014 Jul 4;345(6192):98-101. doi: 10.1126/science.1254312. Science. 2014. PMID: 24994655 Free PMC article.

4

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.

Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Li X, et al. Mol Cancer Ther. 2015 Mar;14(3):642-8. doi: 10.1158/1535-7163.MCT-14-0650. Epub 2015 Jan 6. Mol Cancer Ther. 2015. PMID: 25564440 Free PMC article.

5

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.

Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. Mendez AS, et al. Elife. 2015 May 19;4:e05434. doi: 10.7554/eLife.05434. Elife. 2015. PMID: 25986605 Free PMC article.

6

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.

Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Acosta-Alvear D, et al. Elife. 2015 Sep 1;4:e08153. doi: 10.7554/eLife.08153. Elife. 2015. PMID: 26327694 Free PMC article.

7

A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing.

Peschek J, Acosta-Alvear D, Mendez AS, Walter P. Peschek J, et al. EMBO Rep. 2015 Dec;16(12):1688-98. doi: 10.15252/embr.201540955. Epub 2015 Oct 19. EMBO Rep. 2015. PMID: 26483401 Free PMC article.

8

Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.

Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. Sherbenou DW, et al. J Clin Invest. 2016 Dec 1;126(12):4640-4653. doi: 10.1172/JCI85856. Epub 2016 Nov 14. J Clin Invest. 2016. PMID: 27841764 Free PMC article.

9

Targeting IRE1 with small molecules counteracts progression of atherosclerosis.

Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E. Tufanli O, et al. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1395-E1404. doi: 10.1073/pnas.1621188114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137856 Free PMC article.

10

An unfolded protein-induced conformational switch activates mammalian IRE1.

Karagöz GE, Acosta-Alvear D, Nguyen HT, Lee CP, Chu F, Walter P. Karagöz GE, et al. Elife. 2017 Oct 3;6:e30700. doi: 10.7554/eLife.30700. Elife. 2017. PMID: 28971800 Free PMC article.

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