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Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice.
Cahalan SM, Gonzalez-Cabrera PJ, Sarkisyan G, Nguyen N, Schaeffer MT, Huang L, Yeager A, Clemons B, Scott F, Rosen H. Cahalan SM, et al. Among authors: rosen h. Nat Chem Biol. 2011 May;7(5):254-6. doi: 10.1038/nchembio.547. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445057 Free PMC article.
Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.
Schürer SC, Brown SJ, Gonzalez-Cabrera PJ, Schaeffer MT, Chapman J, Jo E, Chase P, Spicer T, Hodder P, Rosen H. Schürer SC, et al. Among authors: rosen h. ACS Chem Biol. 2008 Aug 15;3(8):486-98. doi: 10.1021/cb800051m. Epub 2008 Jul 1. ACS Chem Biol. 2008. PMID: 18590333 Free PMC article.
Sphingosine 1-phosphate receptor signaling.
Rosen H, Gonzalez-Cabrera PJ, Sanna MG, Brown S. Rosen H, et al. Annu Rev Biochem. 2009;78:743-68. doi: 10.1146/annurev.biochem.78.072407.103733. Annu Rev Biochem. 2009. PMID: 19231986 Review.
Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease.
Karuppuchamy T, Behrens EH, González-Cabrera P, Sarkisyan G, Gima L, Boyer JD, Bamias G, Jedlicka P, Veny M, Clark D, Peach R, Scott F, Rosen H, Rivera-Nieves J. Karuppuchamy T, et al. Among authors: rosen h. Mucosal Immunol. 2017 Jan;10(1):162-171. doi: 10.1038/mi.2016.35. Epub 2016 Apr 6. Mucosal Immunol. 2017. PMID: 27049060 Free PMC article.
1,899 results