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Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A₂A and A₃ adenosine receptor ligands.
Hou X, Majik MS, Kim K, Pyee Y, Lee Y, Alexander V, Chung HJ, Lee HW, Chandra G, Lee JH, Park SG, Choi WJ, Kim HO, Phan K, Gao ZG, Jacobson KA, Choi S, Lee SK, Jeong LS. Hou X, et al. J Med Chem. 2012 Jan 12;55(1):342-56. doi: 10.1021/jm201229j. Epub 2011 Dec 28. J Med Chem. 2012. PMID: 22142423 Free PMC article.
N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the A-region.
Kim YS, Kil MJ, Kang SU, Ryu H, Kim MS, Cho Y, Bhondwe RS, Thorat SA, Sun W, Liu K, Lee JH, Choi S, Pearce LV, Pavlyukovets VA, Morgan MA, Tran R, Lazar J, Blumberg PM, Lee J. Kim YS, et al. Among authors: lee j, lee jh. Bioorg Med Chem. 2012 Jan 1;20(1):215-24. doi: 10.1016/j.bmc.2011.11.008. Epub 2011 Nov 22. Bioorg Med Chem. 2012. PMID: 22169633 Free PMC article.
Heterocycle-linked phenylbenzyl amides as novel TRPV1 antagonists and their TRPV1 binding modes: constraint-induced enhancement of in vitro and in vivo activities.
Kim NJ, Li FN, Lee JH, Park SG, Kim K, Lim C, Han YT, Yun H, Jung JW, Park HG, Kim HD, Woo BY, Shin SS, Kim SY, Choi JK, Jeong YS, Park Y, Park YH, Kim DD, Choi S, Suh YG. Kim NJ, et al. Chem Asian J. 2013 Feb;8(2):400-9. doi: 10.1002/asia.201200730. Epub 2012 Dec 3. Chem Asian J. 2013. PMID: 23208797
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