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Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo.
Crouch E, Nikolaidis N, McCormack FX, McDonald B, Allen K, Rynkiewicz MJ, Cafarella TM, White M, Lewnard K, Leymarie N, Zaia J, Seaton BA, Hartshorn KL. Crouch E, et al. Among authors: hartshorn kl. J Biol Chem. 2011 Nov 25;286(47):40681-92. doi: 10.1074/jbc.M111.300673. Epub 2011 Sep 30. J Biol Chem. 2011. PMID: 21965658 Free PMC article.
Enhanced Antiviral Activity of Human Surfactant Protein D by Site-Specific Engineering of the Carbohydrate Recognition Domain.
van Eijk M, Hillaire MLB, Rimmelzwaan GF, Rynkiewicz MJ, White MR, Hartshorn KL, Hessing M, Koolmees PA, Tersteeg MH, van Es MH, Meijerhof T, Huckriede A, Haagsman HP. van Eijk M, et al. Among authors: hartshorn kl. Front Immunol. 2019 Oct 22;10:2476. doi: 10.3389/fimmu.2019.02476. eCollection 2019. Front Immunol. 2019. PMID: 31749796 Free PMC article.
171 results