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Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.
Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY. Chan AC, et al. Among authors: grossmann ah. J Clin Invest. 2011 May;121(5):1871-81. doi: 10.1172/JCI44393. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490399 Free PMC article.
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY. Gibson CC, et al. Among authors: grossmann ah. Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8. Circulation. 2015. PMID: 25486933 Free PMC article.
The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
Yoo JH, Brady SW, Acosta-Alvarez L, Rogers A, Peng J, Sorensen LK, Wolff RK, Mleynek T, Shin D, Rich CP, Kircher DA, Bild A, Odelberg SJ, Li DY, Holmen SL, Grossmann AH. Yoo JH, et al. Among authors: grossmann ah. Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2. Cancer Res. 2019. PMID: 31048499 Free PMC article.
ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.
Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY. Yoo JH, et al. Among authors: grossmann ah. Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2. Cancer Cell. 2016. PMID: 27265506 Free PMC article.
NF1 Somatic Mutation in Dystrophic Scoliosis.
Margraf RL, VanSant-Webb C, Mao R, Viskochil DH, Carey J, Hanson H, D'Astous J, Grossmann A, Stevenson DA. Margraf RL, et al. J Mol Neurosci. 2019 May;68(1):11-18. doi: 10.1007/s12031-019-01277-0. Epub 2019 Feb 18. J Mol Neurosci. 2019. PMID: 30778836
40 results