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Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Gloeckner C, et al. Among authors: tricoche n. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3424-9. doi: 10.1073/pnas.0915125107. Epub 2010 Feb 8. Proc Natl Acad Sci U S A. 2010. PMID: 20142509 Free PMC article.
Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.
Bulman CA, Bidlow CM, Lustigman S, Cho-Ngwa F, Williams D, Rascón AA Jr, Tricoche N, Samje M, Bell A, Suzuki B, Lim KC, Supakorndej N, Supakorndej P, Wolfe AR, Knudsen GM, Chen S, Wilson C, Ang KH, Arkin M, Gut J, Franklin C, Marcellino C, McKerrow JH, Debnath A, Sakanari JA. Bulman CA, et al. Among authors: tricoche n. PLoS Negl Trop Dis. 2015 Feb 20;9(2):e0003534. doi: 10.1371/journal.pntd.0003534. eCollection 2015 Feb. PLoS Negl Trop Dis. 2015. PMID: 25700363 Free PMC article.
Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.
Voronin D, Tricoche N, Jawahar S, Shlossman M, Bulman CA, Fischer C, Suderman MT, Sakanari JA, Lustigman S. Voronin D, et al. Among authors: tricoche n. PLoS Negl Trop Dis. 2019 Jan 17;13(1):e0007108. doi: 10.1371/journal.pntd.0007108. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30653499 Free PMC article.
Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.
George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. George PJ, et al. Among authors: tricoche n. PLoS Negl Trop Dis. 2019 Sep 16;13(9):e0007730. doi: 10.1371/journal.pntd.0007730. eCollection 2019 Sep. PLoS Negl Trop Dis. 2019. PMID: 31525197 Free PMC article.
Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models.
Hübner MP, Gunderson E, Vogel I, Bulman CA, Lim KC, Koschel M, Ehrens A, Frohberger SJ, Fendler M, Tricoche N, Voronin D, Steven A, Chi V, Bakowski MA, Woods AK, Petrassi HM, McNamara CW, Beerntsen B, Chappell L, Sullivan W, Taylor MJ, Turner JD, Hoerauf A, Lustigman S, Sakanari JA. Hübner MP, et al. Among authors: tricoche n. Int J Parasitol Drugs Drug Resist. 2020 Apr;12:18-27. doi: 10.1016/j.ijpddr.2019.12.001. Epub 2019 Dec 10. Int J Parasitol Drugs Drug Resist. 2020. PMID: 31869759 Free PMC article.
Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs.
Carter DS, Jacobs RT, Freund YR, Berry PW, Akama T, Easom EE, Lunde CS, Rock F, Stefanakis R, McKerrow J, Fischer C, Bulman CA, Lim KC, Suzuki BM, Tricoche N, Sakanari JA, Lustigman S, Plattner JJ. Carter DS, et al. Among authors: tricoche n. ACS Infect Dis. 2020 Feb 14;6(2):180-185. doi: 10.1021/acsinfecdis.9b00397. Epub 2020 Jan 28. ACS Infect Dis. 2020. PMID: 31876143 Free PMC article.
35 results