Jorgensen WT - Search Results

1

Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity.

Banister SD, Moussa IA, Jorgensen WT, Chua SW, Kassiou M. Banister SD, et al. Among authors: jorgensen wt. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3622-6. doi: 10.1016/j.bmcl.2011.04.098. Epub 2011 Apr 28. Bioorg Med Chem Lett. 2011. PMID: 21555222

2

Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands.

Banister SD, Moussa IA, Beinat C, Reynolds AJ, Schiavini P, Jorgensen WT, Kassiou M. Banister SD, et al. Among authors: jorgensen wt. Bioorg Med Chem Lett. 2011 Jan 1;21(1):38-41. doi: 10.1016/j.bmcl.2010.11.075. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21146989

3

The nonpeptide oxytocin receptor agonist WAY 267,464: receptor-binding profile, prosocial effects and distribution of c-Fos expression in adolescent rats.

Hicks C, Jorgensen W, Brown C, Fardell J, Koehbach J, Gruber CW, Kassiou M, Hunt GE, McGregor IS. Hicks C, et al. J Neuroendocrinol. 2012 Jul;24(7):1012-29. doi: 10.1111/j.1365-2826.2012.02311.x. J Neuroendocrinol. 2012. PMID: 22420322 Free PMC article.

4

Flexible analogues of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin 1a receptors.

Jorgensen WT, Gulliver DW, Werry EL, Reekie T, Connor M, Kassiou M. Jorgensen WT, et al. Eur J Med Chem. 2016 Jan 27;108:730-740. doi: 10.1016/j.ejmech.2015.11.050. Epub 2015 Dec 13. Eur J Med Chem. 2016. PMID: 26741855

5

The Formation of Seven-Membered Heterocycles under Mild Pictet-Spengler Conditions: A Route to Pyrazolo[3,4]benzodiazepines.

Katte TA, Reekie TA, Jorgensen WT, Kassiou M. Katte TA, et al. Among authors: jorgensen wt. J Org Chem. 2016 Jun 3;81(11):4883-9. doi: 10.1021/acs.joc.6b00710. Epub 2016 May 13. J Org Chem. 2016. PMID: 27159074

6

Investigation of pyrazolo-sulfonamides as putative small molecule oxytocin receptor agonists.

Katte TA, Reekie TA, Werry EL, Jorgensen WT, Boyd R, Wong ECN, Gulliver DW, Connor M, Kassiou M. Katte TA, et al. Among authors: jorgensen wt. Eur J Med Chem. 2017 Aug 18;136:330-333. doi: 10.1016/j.ejmech.2017.05.013. Epub 2017 May 4. Eur J Med Chem. 2017. PMID: 28505537

7

Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors.

Jorgensen WT, Gulliver DW, Katte TA, Werry EL, Reekie TA, Connor M, Kassiou M. Jorgensen WT, et al. Eur J Med Chem. 2018 Jan 1;143:1644-1656. doi: 10.1016/j.ejmech.2017.10.059. Epub 2017 Oct 23. Eur J Med Chem. 2018. PMID: 29126725

8

Targeting the Oxytocin System: New Pharmacotherapeutic Approaches.

Gulliver D, Werry E, Reekie TA, Katte TA, Jorgensen W, Kassiou M. Gulliver D, et al. Trends Pharmacol Sci. 2019 Jan;40(1):22-37. doi: 10.1016/j.tips.2018.11.001. Epub 2018 Nov 30. Trends Pharmacol Sci. 2019. PMID: 30509888 Review.

9

Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (Ca_V3) Inhibitors.

Kevin RC, Mirlohi S, Manning JJ, Boyd R, Cairns EA, Ametovski A, Lai F, Luo JL, Jorgensen W, Ellison R, Gerona RR, Hibbs DE, McGregor IS, Glass M, Connor M, Bladen C, Zamponi GW, Banister SD. Kevin RC, et al. ACS Chem Neurosci. 2022 May 4;13(9):1395-1409. doi: 10.1021/acschemneuro.1c00822. Epub 2022 Apr 20. ACS Chem Neurosci. 2022. PMID: 35442021

10

Understanding In Vitro Pathways to Drug Discovery for TDP-43 Proteinopathies.

Cheng HWA, Callis TB, Montgomery AP, Danon JJ, Jorgensen WT, Ke YD, Ittner LM, Werry EL, Kassiou M. Cheng HWA, et al. Among authors: jorgensen wt. Int J Mol Sci. 2022 Nov 25;23(23):14769. doi: 10.3390/ijms232314769. Int J Mol Sci. 2022. PMID: 36499097 Free PMC article.

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