Wolf CR - Search Results

1

The imidazoacridinone antitumor drug, C-1311, is metabolized by flavin monooxygenases but not by cytochrome P450s.

Potega A, Dabrowska E, Niemira M, Kot-Wasik A, Ronseaux S, Henderson CJ, Wolf CR, Mazerska Z. Potega A, et al. Among authors: wolf cr. Drug Metab Dispos. 2011 Aug;39(8):1423-32. doi: 10.1124/dmd.111.038984. Epub 2011 May 9. Drug Metab Dispos. 2011. PMID: 21555506

2

A role for cytochrome b5 in the In vivo disposition of anticancer and cytochrome P450 probe drugs in mice.

Henderson CJ, McLaughlin LA, Finn RD, Ronseaux S, Kapelyukh Y, Wolf CR. Henderson CJ, et al. Among authors: wolf cr. Drug Metab Dispos. 2014 Jan;42(1):70-7. doi: 10.1124/dmd.113.055277. Epub 2013 Oct 10. Drug Metab Dispos. 2014. PMID: 24115751 Free PMC article.

3

Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.

McLaughlin LA, Dickmann LJ, Wolf CR, Henderson CJ. McLaughlin LA, et al. Among authors: wolf cr. Drug Metab Dispos. 2008 Jul;36(7):1322-31. doi: 10.1124/dmd.108.021261. Epub 2008 Apr 17. Drug Metab Dispos. 2008. PMID: 18420780

4

Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.

Finn RD, McLaughlin LA, Ronseaux S, Rosewell I, Houston JB, Henderson CJ, Wolf CR. Finn RD, et al. Among authors: wolf cr. J Biol Chem. 2008 Nov 14;283(46):31385-93. doi: 10.1074/jbc.M803496200. Epub 2008 Sep 19. J Biol Chem. 2008. PMID: 18805792 Free PMC article.

5

Knockout and transgenic mice in glutathione transferase research.

Henderson CJ, Wolf CR. Henderson CJ, et al. Among authors: wolf cr. Drug Metab Rev. 2011 May;43(2):152-64. doi: 10.3109/03602532.2011.562900. Epub 2011 Mar 22. Drug Metab Rev. 2011. PMID: 21425933 Review.

6

Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice.

Arlt VM, Singh R, Stiborová M, Gamboa da Costa G, Frei E, Evans JD, Farmer PB, Wolf CR, Henderson CJ, Phillips DH. Arlt VM, et al. Among authors: wolf cr. Drug Metab Dispos. 2011 Dec;39(12):2169-73. doi: 10.1124/dmd.111.041343. Epub 2011 Sep 22. Drug Metab Dispos. 2011. PMID: 21940903

7

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

Riddick DS, Ding X, Wolf CR, Porter TD, Pandey AV, Zhang QY, Gu J, Finn RD, Ronseaux S, McLaughlin LA, Henderson CJ, Zou L, Flück CE. Riddick DS, et al. Among authors: wolf cr. Drug Metab Dispos. 2013 Jan;41(1):12-23. doi: 10.1124/dmd.112.048991. Epub 2012 Oct 19. Drug Metab Dispos. 2013. PMID: 23086197 Free PMC article.

8

Evidence that cytochrome b5 and cytochrome b5 reductase can act as sole electron donors to the hepatic cytochrome P450 system.

Henderson CJ, McLaughlin LA, Wolf CR. Henderson CJ, et al. Among authors: wolf cr. Mol Pharmacol. 2013 Jun;83(6):1209-17. doi: 10.1124/mol.112.084616. Epub 2013 Mar 25. Mol Pharmacol. 2013. PMID: 23530090

9

Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism.

Scheer N, McLaughlin LA, Rode A, Macleod AK, Henderson CJ, Wolf CR. Scheer N, et al. Among authors: wolf cr. Drug Metab Dispos. 2014 Jun;42(6):1022-30. doi: 10.1124/dmd.114.057885. Epub 2014 Mar 26. Drug Metab Dispos. 2014. PMID: 24671958

10

The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function.

Scott EE, Wolf CR, Otyepka M, Humphreys SC, Reed JR, Henderson CJ, McLaughlin LA, Paloncýová M, Navrátilová V, Berka K, Anzenbacher P, Dahal UP, Barnaba C, Brozik JA, Jones JP, Estrada DF, Laurence JS, Park JW, Backes WL. Scott EE, et al. Among authors: wolf cr. Drug Metab Dispos. 2016 Apr;44(4):576-90. doi: 10.1124/dmd.115.068569. Epub 2016 Feb 5. Drug Metab Dispos. 2016. PMID: 26851242 Free PMC article. Review.

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