Kaufman RJ - Search Results

1

Eukaryotic initiation factor 2alpha phosphorylation is required for B-cell maturation and function in mice.

Mielke N, Schwarzer R, Calkhoven CF, Kaufman RJ, Dörken B, Leutz A, Jundt F. Mielke N, et al. Among authors: kaufman rj. Haematologica. 2011 Sep;96(9):1261-8. doi: 10.3324/haematol.2011.042853. Epub 2011 May 12. Haematologica. 2011. PMID: 21565905 Free PMC article.

2

Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.

Sadleir KR, Eimer WA, Kaufman RJ, Osten P, Vassar R. Sadleir KR, et al. Among authors: kaufman rj. PLoS One. 2014 Jul 3;9(7):e101643. doi: 10.1371/journal.pone.0101643. eCollection 2014. PLoS One. 2014. PMID: 24992504 Free PMC article.

3

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H, Ogawa S, Kaufman RJ, Kominami E, Momoi T. Kouroku Y, et al. Among authors: kaufman rj. Cell Death Differ. 2007 Feb;14(2):230-9. doi: 10.1038/sj.cdd.4401984. Epub 2006 Jun 23. Cell Death Differ. 2007. PMID: 16794605

4

Stress-induced apoptosis in Spodoptera frugiperda (Sf9) cells: baculovirus p35 mitigates eIF2 alpha phosphorylation.

Aparna G, Bhuyan AK, Sahdev S, Hasnain SE, Kaufman RJ, Ramaiah KV. Aparna G, et al. Among authors: kaufman rj. Biochemistry. 2003 Dec 30;42(51):15352-60. doi: 10.1021/bi0349423. Biochemistry. 2003. PMID: 14690445

5

eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory.

Costa-Mattioli M, Gobert D, Stern E, Gamache K, Colina R, Cuello C, Sossin W, Kaufman R, Pelletier J, Rosenblum K, Krnjević K, Lacaille JC, Nader K, Sonenberg N. Costa-Mattioli M, et al. Cell. 2007 Apr 6;129(1):195-206. doi: 10.1016/j.cell.2007.01.050. Cell. 2007. PMID: 17418795 Free PMC article.

6

IRE1α Mediates the Hypertrophic Growth of Cardiomyocytes Through Facilitating the Formation of Initiation Complex to Promote the Translation of TOP-Motif Transcripts.

Li C, Li S, Zhang G, Li Q, Song W, Wang X, Cook JA, van der Stoel M, Wright BW, Altamirano F, Niewold EL, Han J, Kimble G, Zhang P, Luo X, Urra H, May HI, Ferdous A, Sun XN, Deng Y, Ikonen E, Hetz C, Kaufman RJ, Zhang K, Gillette TG, Scherer PE, Hill JA, Chen J, Wang ZV. Li C, et al. Among authors: kaufman rj. Circulation. 2024 Jun 5. doi: 10.1161/CIRCULATIONAHA.123.067606. Online ahead of print. Circulation. 2024. PMID: 38836349 Free article.

7

The IRE1α/XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease.

Cao S, Fachi JL, Ma K, Ulezko Antonova A, Wang Q, Cai Z, Kaufman RJ, Ciorba MA, Deepak P, Colonna M. Cao S, et al. Among authors: kaufman rj. J Clin Invest. 2024 May 9:e174198. doi: 10.1172/JCI174198. Online ahead of print. J Clin Invest. 2024. PMID: 38722686 Free article.

8

Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.

Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Among authors: kaufman rj. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.

9

ATF6 protects against protein misfolding during cardiac hypertrophy.

Hofmann C, Aghajani M, Alcock CD, Blackwood EA, Sandmann C, Herzog N, Groß J, Plate L, Wiseman RL, Kaufman RJ, Katus HA, Jakobi T, Völkers M, Glembotski CC, Doroudgar S. Hofmann C, et al. Among authors: kaufman rj. J Mol Cell Cardiol. 2024 Apr;189:12-24. doi: 10.1016/j.yjmcc.2024.02.001. Epub 2024 Feb 23. J Mol Cell Cardiol. 2024. PMID: 38401179

10

Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.

Chen Z, Wang S, Pottekat A, Duffey A, Jang I, Chang BH, Cho J, Finck BN, Davidson NO, Kaufman RJ. Chen Z, et al. Among authors: kaufman rj. Mol Metab. 2024 Feb;80:101874. doi: 10.1016/j.molmet.2024.101874. Epub 2024 Jan 9. Mol Metab. 2024. PMID: 38211723 Free PMC article.

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