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Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Gornalusse GG, et al. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4762-71. doi: 10.1073/pnas.1423228112. Epub 2015 Aug 11. Proc Natl Acad Sci U S A. 2015. PMID: 26307764 Free PMC article.
HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids.
Kasprowicz VO, Cheng TY, Ndung'u T, Sunpath H, Moody DB, Kasmar AG. Kasprowicz VO, et al. J Infect Dis. 2016 Feb 15;213(4):628-33. doi: 10.1093/infdis/jiv455. Epub 2015 Sep 15. J Infect Dis. 2016. PMID: 26374910 Free PMC article.
HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults.
Matthews PC, Carlson JM, Beloukas A, Malik A, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jesuthasan G, Jeffery K, Jojic N, Ndung'u T, Carrington M, Goulder PJ, Geretti AM, Klenerman P. Matthews PC, et al. J Infect Dis. 2016 Apr 15;213(8):1248-52. doi: 10.1093/infdis/jiv592. Epub 2015 Dec 9. J Infect Dis. 2016. PMID: 26655301 Free PMC article.
Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.
Naranbhai V, de Assis Rosa D, Werner L, Moodley R, Hong H, Kharsany A, Mlisana K, Sibeko S, Garrett N, Chopera D, Carr WH, Abdool Karim Q, Hill AV, Abdool Karim SS, Altfeld M, Gray CM, Ndung'u T. Naranbhai V, et al. BMC Infect Dis. 2016 Jan 25;16:27. doi: 10.1186/s12879-016-1361-1. BMC Infect Dis. 2016. PMID: 26809736 Free PMC article.
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.
Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. Ramsuran V, et al. Science. 2018 Jan 5;359(6371):86-90. doi: 10.1126/science.aam8825. Epub 2018 Jan 4. Science. 2018. PMID: 29302013 Free PMC article.
337 results